Mushroom poisoning occurs frequently all over the world,which has become one of the most common food poisoning events,as well as the main cause of death from food poisoning.Meanwhile,the most and deadliest toxin in the poisonous mushroom is amatoxin.Hence,rapid and accurate detection of amanitin is of great significance for the identification of toxic source,and the subsequent treatment and prevention of patients.At present,the common methods for amanitin detection include chromatography-mass spectrometry and some other detection techniques based on immune recognition and special chemical structures.It is still the focus of current research that the development of new detection methods with strong specificity,high sensitivity and low time consumption.Therefore,the detection methods of amanitin are reviewed in this paper in order to arouse the attention of research colleagues in this field and stimulate more research ideas.