A micellar electrokinetic capillary chromatographic method was established for the simultaneous determination of rutin,danshensu,ginsenoside Rb1,ginsenoside Rg1 and notoginsenoside R1 in Xiaoshuantongluo Tablet.The sample was extracted with methanol and separated on an uncoated fused silica capillary column(75 μm×60 cm,effective length 50 cm),using 60 mmol/L SDS-30 mmol/L Tris-10 mmol/L H3BO3(containing 15% methanol) as running buffer,with applied voltage of 25 kV.The analytes were detected by UV detecter at 214 nm.Under the optimized conditions,a baseline separation of five components was achieved in 26 min.The calibration curves were linear in the ranges of 2.5-100 mg/L for rutin,2.5-200 mg/L for sodium danshensu,10-300 mg/L for ginsenoside Rb1,15-400 mg/L for ginsenoside Rg1 and notoginsenoside R1,with detection limits of 0.3,0.9,3.0,5.0,6.0 mg/L,respectively.The average recoveries of five components were between 93% and 108% with relative standard deviations not more than 4.5%.The method was simple and accurate,and was suitable for the routine analysis of five effective components in Xiaoshuantongluo Tablet.