A rapid，sensitive and accurate method was developed for the simultaneous determination of 6 kinds of phthalic acid esters（PAEs）in wine samples by dispersive magnetic solid phase extraction coupled with high performance liquid chromatography（dMSPE/HPLC）.The wine samples were concentrated with polystyrene nano-magnetic materials，then separated on a C8 analytical column（250 mm×4.6 mm×5 μm） using methanol-water as mobile phase by gradient elution，and detected at 230 nm via UV detector.The results showed that，under the optimal condition，good linearities for the target PAEs were obtained between 2 ng/L and 500 ng/L with correlation coefficients（r2） not less than 0.997 9.The spiked recoveries were between 85.2% and 101.2% with relative standard deviations（RSDs） of 0.8%-9.2%.The limits of detection（LODs） were in the range of 0.22-4.5 ng/L and the limits of quantitation（LOQs） were 1.2-10 ng/L.The developed method could be applied in the routine analyses on PAEs in wine samples.