Magnetic solid-phase extraction(MSPE)is a novel sample preparation technique using magnetic materials as sorbents,which can be quickly separated from sample solution under external magnetic field.The development of new magnetic sorbents has become a subject of great interest in the MSPE field.MSPE using ionic liquid(IL)modified magnetic particles as sorbent has attracted more and more attention in the extraction and separation of trace or ultra trace organic pollutants and inorganic ions in food,environmental and biological samples.The technique possesses some advantages of MSPE such as simple operation,quick extraction and low matrix interference,as well as unique characteristics of IL including tailored structure and easy chemical functionalization. Some preparation methods of IL modified magnetic materials are provided,including physical coating method,chemical bonding method and embedding method,and some extraction modes of IL-MSPE such as traditional MSPE,mixed hemimicelles based MSPE and dispersive liquid-liquid microextraction based MSPE. The applications of IL-MSPE as a sample preparation in the extraction and separation of organic pollutants,metal ions and biological molecules using chromatography and spectroscopy techniques in the latest 5 years are reviewed,and the future trends of IL-MSPE technique are also discussed.