With the advantages of high selective discrimination,good stability and simple preparation, the molecular imprinted polymers(MIPs) can be modified on surface plasmon resonance sensors,in order to study the binding properties and interactions between molecules.The sensitivity of surface plasmon resonance(SPR) sensors,based on molecular imprinted technology(MIP-SPR),was improved a lot with applications of quantum dot and other nanomaterials like graphene,and therefore,promoting the application of this technology in the food safety analysis.In this paper,the preparation technologies,analysis principles and advantages of MIP-SPR sensors were briefly introduced,and its new applications in food safety were deeply analyzed.Finally,the development trends of MIP-SPR sensors were discussed.