Preparation of a silica based sulfonated hypercrosslinked polystyrene-divinylbenzene strong cation exchanger was reported.Silica beads of an average particle size of approximately 5 μm were first reacted with divinyltetramethyl disiloxane to prepare the vinylated silica phase.The vinylated silica phase was then copolymerized with a monomer mixture of styrene-divinylbenzene(2∶1),and the hypercrosslinked polystyrene-divinylbenzene(HCL PS-DVB)derivated silica phase was prepared.And at last,the HCL PS-DVB silica phase was sulfonated to prepare the cation exchanger in an ice water bath.The strong cation-exchanger was characterized using infrared spectra.The cation-exchanger was proved to be stable in extreme acidic and in extreme basic solutions.The strong cation-exchanger was applied in the separation of basic organics with a good separation result.