An economic and facile preparation nonenzymatic uric acid sensor was successfully fabricated by electrodeposition of copper on SWNTs/Nafion modified glassy carbon electrode.The morphology of the material was observed by scanning electron microscopy(SEM),and the element composition of the material was investigated by energy dispersive X-ray spectroscopy(EDX).Effects of various scan rates and pH conditions on the modified electrode were investigated.The linear range of detected UA was in the range of 0.1-1 000 μmol?L-1 and the limit of detection(LOD,S/N=3) was 0.058 5μmol?L-1.The sensor was applied in the detection of UA in human serum by the standard addition method with recoveries of 97.2%-103.9% and relative standard deviation(RSD)of 0.04%-0.11%.The results of the nonenzymatic method are highly consistent with that of the GOD-POD enzymatic method.The sensor shows the advantages of facile fabrication,high sensitivity,good stability and high reproducibility.
关键词
单壁碳纳米管尿酸传感器纳米铜全氟聚苯乙烯磺酸
Keywords
single walled carbon nanotubes(SWNTs)uric-acid(UA)sensorcopper nanoparticles(CuNPs)Nafion