Dispersive liquid-liquid microextraction(DLLME) is a novel sample preparation technique,which is based on the traditional liquid-liquid extraction.In the past few years,it has always grabbed the attention of researchers in the field of separation and analysis for the merit of utilization of μL level of extraction solvent,and it also shows a superior separation efficiency and a strong enrichment ability.In this paper,low toxic extractant solvents such like low density solvent,auxiliary solvent,back extraction solvent and ionic liquid,and the relevant microextraction mode,such as utilizing self made devices,solvent demulsification,solidification of a floating organic drop,uxiliary solvent extraction,back extraction and ionic liquid based DLLME were briefly reviewed according to the selection of extraction solvent.In the end,extraction characteristics of DLLME combined with other extraction techniques like liquid-liquid extraction,solid-phase extraction,solid-phase microextraction,dispersive solid-phase extraction,matrix solid phase dispersion extraction,super critical extraction,ultrasonic assisted extraction were also briefly reviewed.