An analytical method for the simultaneous determination of 67 pesticides in vegetables and fruits by gas chromatography-triple quadrupole mass spectrometry（GC-MS/MS） with dispersive solid phase extraction（QuEChERS）.The samples were extracted with acetonitrile（containing 1% acetic acid），and then cleaned up with dispersive solid phase extraction.The extracts were determined by GC-MS/MS in multi-reaction monitoring(MRM) mode with the external standard method. The calibration curves of 67 pecitides were linear in the range of 0.005-0.24μg/mL with correlation coefficients（r2） higher than 0.99.The average recoveries at spiked concentration levels of 0.02，0.06，0.12mg/kg ranged from 60.3% to 119.8% with relative standard deviations（RSDs） of 0.5%-14.7%.The limits of detection（LOD） for the method were in the range of 0.0001-0.003mg/kg.The limits of quantitations（LOQs） were 0.0002-0.009mg/kg.The method was applied in the detection of pesticide residues of vegetables and fruits，and the result was more satisfactory comparing with that of GC，GCP/GC-MS，LC-MS/MS methods. The method showed the advantages of simplicity, quickness, high sensitivity，good selectivity，good reproducibility and stability，and was suitable for the analysis of pesticide residues in daily vegetables and fruits.