The concentrations of heavy metals（Cd，Cr，Cu，Fe，Mn，Ni，Pb，Sr，Zn） in several South China Medicines were investigated，the speciation of heavy metals were analyzed by the continuous extraction method，and the impact of decoction on contents and speciation of heavy metals were also studied.The results showed that，the concentrations of Cr，Pb，Zn were high in several medical herbs，and the total concentrations of heavy metals in Morinda officinalis were higher than the values of the limit standard.Cr，Cu，Mn，Ni，Pb and Zn in raw medicinal herbs mainly existed as the organic fraction and residual fraction，Fe and Sr mainly existed as residual fraction.A large amount of heavy metals in South China Medicine released to the medicine soup by decocting.Cu，Mn，Cr，Pb and Zn in medicine soup mainly derived from the exchangeable，carbonate bound and organic speciation in the medicinal herbs.Sr，Ni and Fe in medicine soup mainly derived from their residual fraction.The total concentrations and non residual amounts of Cu，Mn，Cr，Pb and Zn were required to keep in control to reduce the concentrations of heavy metals in the medicine soup，and the total concentrations of Fe，Ni and Sr were required to be in control in minority herbs.