A rapid method was developed for the determination of 10 organophosphate esters(OPEs) in the Arctic waters by liquid chromatography-mass spectrometry(LC-MS/MS) combined with C18membrane disk extraction.By the optimized pretreatment and instrumental methods,10 OPEs were collected with C18membrane disk from 4 L water,and extracted with dichloromethane in ultrasonic extraction apparatus.After purification and concentration,the OPEs were analyzed by LC-MS/MS under positive electrospray ionization in selective reaction monitoring(SRM) mode.The linear correlation coefficients are in the range of 0.994 4-0.999 9.The recoveries of 10 OPEs in water samples ranged from 64.1% to 115% with the method detection limits of 0.08-0.55 ng/L.Furthermore,10 OPEs compounds in the Arctic waters samples were analyzed by this method,and the OPEs concentrations in the river and seawater were in the ranges of 0.64-6.64 ng/L and 0.09-2.03 ng/L,respectively.