With the advantages of small size,portabilityand anti-electromagnetic interference,fiber optic surface plasmon resonance(FO-SPR) biosensor could be applied in biological,chemical,pharmaceutical and food detections.In this paper,the recent progresses on the structures,film components and new applications of FO-SPR biosensor are summarized .In general,the reflection type and online transmission type are the two most important structures of the biosensor.Moreover,the commonly used films are gold film,silver film,composite film and metal nanoparticles.Based on the features of real-time analysis,anti-electromagnetic interference and multichannel detection,the future development and applications of FO-SPR biosensor are put forward.