Investigation on Degradation of Dicofol in Gas Chromatography System

QIAN Zhen-jie; WANG Yu; ZHAO Jin-li; WANG Cheng-long; HUANG Song; TAN Jin-ping; HUANG Xiao-qing; LIN Ze-shan; LIU Jia

doi:10.19969/j.fxcsxb.22062905

您当前的位置：

首页 >

文章列表页 >

Investigation on Degradation of Dicofol in Gas Chromatography System

Special Column for DRE Thesis Competition | 更新时间：2023-01-04

- Investigation on Degradation of Dicofol in Gas Chromatography System
- Journal of Instrumental Analysis Vol. 41, Issue 12, Pages: 1765-1772(2022)
- 作者机构：
  
  广州市食品检验所，广东广州 511400
- 作者简介：
- 基金信息：
- DOI：10.19969/j.fxcsxb.22062905
  CLC：
扫描看全文
钱振杰,王宇,赵金利等.三氯杀螨醇在气相色谱系统中的降解研究[J].分析测试学报,2022,41(12):1765-1772.

QIAN Zhen-jie,WANG Yu,ZHAO Jin-li,et al.Investigation on Degradation of Dicofol in Gas Chromatography System[J].Journal of Instrumental Analysis,2022,41(12):1765-1772.
钱振杰,王宇,赵金利等.三氯杀螨醇在气相色谱系统中的降解研究[J].分析测试学报,2022,41(12):1765-1772. DOI： 10.19969/j.fxcsxb.22062905.

QIAN Zhen-jie,WANG Yu,ZHAO Jin-li,et al.Investigation on Degradation of Dicofol in Gas Chromatography System[J].Journal of Instrumental Analysis,2022,41(12):1765-1772. DOI： 10.19969/j.fxcsxb.22062905.

摘要

采用气相色谱系统，识别和推测了三氯杀螨醇的主要降解产物及其结构，研究了其在进样口和有机溶剂中的降解行为，并提出了解决降解影响的措施。结果表明，三氯杀螨醇主要的降解产物除4，4'-二氯二苯甲酮（4，4'-DBP）外，还存在一种通过脱氯途径生成的降解物。当进样口温度低于260 ℃时，三氯杀螨醇基本保持稳定；三氯杀螨醇在甲苯中的稳定性较好，在丙酮和乙腈中则完全降解成4，4'-DBP，而对溶剂脱水可减缓该反应的发生；在乙酸乙酯中三氯杀螨醇通过脱氯途径部分降解，在溶剂中添加卤代物可抑制该反应的发生。由于样品基质极性的不确定性，最终选取三氯杀螨醇、4，4'-DBP及脱氯降解物为标志物，以三者峰面积加和的方式对样品中三氯杀螨醇的残留量进行定量分析。采用该方法测得油麦菜、苹果和红茶3种不同基质在0.01、0.05、0.1 mg/kg加标水平下的平均回收率为72.5% ~ 110%，相对标准偏差（RSD，,n, = 6）为5.1% ~ 10%。该研究为三氯杀螨醇的准确定性和定量测定提供了实验依据，并对探索同类结构化合物的降解行为具有参考价值。

Abstract

Gas chromatography system was utilized to identify the main degradation products and structures of dicofol．Its degradation behaviors in the inlet and organic solvents were investigatied and the measures to minimize the degradation effects on the analysis were proposed．The results showed that the main degradation products of dicofol，in addition to the reported 4，4'-DBP，were obtained through the de-chlorination pathway．Generally，dicofol is stable when the inlet temperature is lower than 260 ℃，and it is stable in toluene but completely degrade to 4，4'-DBP in acetone and acetonitrile．Meanwhule，anhydrous solvent could slow down the degradation process．In ethyl acetate，dicofol could be partly degraded by dechlorination．The addition of halides to the solvent could prohibit the dechlorination．Dicofol，4，4'-DBP and degraded products were used to determine the residual amount of dicofol in the actual sample matrix by measuring the sum of the three peak areas due to the uncertainty of the sample matrix polarity．The average recoveries of this method for three matrixes at 0.01，0.05 and 0.1 mg/kg spiked levels ranged from 72.5% to 110%，with the relative standard deviations（RSDs，,n ,= 6） of 5.1%－10%．This study provides an experimental basis for accurate，qualitative and quantitative detection of dicofol，which is of a certain reference value for exploring the degradation of compounds with the smilar structure.

关键词

三氯杀螨醇降解进样口温度溶剂定量气相色谱系统

Keywords

dicofoldegradationthe temperature of the inletsolventquantificationgas chromatography system

references

Reddy N S，Reddy N L，Nissy S M，Pallavi G，Vangalapati M．Materials Today：Proceedings，2020，26：1694－1700.

Li L，Liu J G，Hu J X．Environ. Sci. Technol.，2015，49（1）：212－222.

Eng A，Su K，Harner T，Pozo K，Sinha R K，Sengupta B，Loewen M．Environ. Sci. Technol. Lett.，2016，3（4）：150－155.

UNEP/POPS/POPRC.10/4. Proposal to List Dicofol in Annexes A，B and/or C to the Stockholm Convention on Persistent Organic Pollutants. UNEP，2014.

EPA 738－R－98－018. US EPA’s Registration Eligibility Document for Dicofol，1998. https：//nepis.epa.gov/Exe/ZyPDF.cgi？Dockey=20000Q8G.PDFhttps://nepis.epa.gov/Exe/ZyPDF.cgi?Dockey=20000Q8G.PDF.

Panda D，Manickam S．Ultrason. Sonochem.，2019，51：526－532.

Maštovská K，Lehotay S J．J. Chromatogr. A，2004，1040（2）：259－272.

Dai H，Peng S H，Yuan Z N．J. Instrum. Anal. （戴华，彭三和，袁智能．分析测试学报），1995，14（6）：79－81.

Yu B B，Zeng J B，Gong L F，Yang X Q，Zhang L M，Chen X．Chin. Sci. Bull.，2008，53（1）：27－32.

Panda D，Manickam S．Chemosphere，2018，204：101－108.

Thirugnanasambandham K，Rama R K．Adv. Environ. Technol.，2022，8（1）：1－14.

Wang Z Y，Yang T，Zhai Z H，Zhang B Y，Zhang J B．J. Environ. Sci.，2015，36：22－28.

Dang J，Tian S，Zhang Q Z．Chemosphere，2019，219：645－654.

Lehotay S J．J. AOAC Int.，2005，88（2）：595－612.

GB 2763－2021. National Standards of Food Safty. Maximum Residue Limits for Pesticides in Food. National Standards of the People’s Republic of China（食品安全国家标准．食品中农药最大残留限量．中华人民共和国国家标准）.

GB 23200.113－2018. National Standards of Food Safty. ofDetermination 208 Pesticides and Metabolites Residues in Foods of Plant Origin－Gas Chromatography－Tandem Mass Spectrometry Method. National Standards of the People’s Republic of China （食品安全国家标准．植物源性食品中208种农药及其代谢物残留量的测定—气相色谱－质谱联用法．中华人民共和国国家标准）.

Cui X，Zhong Q，Zhang X Z，Li H X，Wang X R，Luo F J，Cheng Y P，Chen Z M．J. Instrum. Anal. 崔璇，钟青，张新忠，黎洪霞，王新茹，罗逢健，程有普，陈宗懋．分析测试学报），2019，38（2）：249－262.

Ren X H，Sun Y M，Zhu L，Cui Z J．Comput. Theoret. Chem.，2011，963：365－370.

He J D．Chin. J. Tropic. Agric. Eng. （何继东．热带农业工程），2020，44（5）：51－52.

Zhang X Z，Ma X D，Zhang W G，Lin J，Li C J．Chin. J. Anal. Chem. （张新忠，马晓东，张伟国，林健，李重九．分析化学），2008，36（6）：249－262.

Xing Q Y，Pei W W，Xu R Q，Pei J．Basic Organic Chemistry. 4th ed. Beijing：Peking University Press（邢其毅，裴伟伟，徐瑞秋，裴坚．基础有机化学．第四版．北京：北京大学出版社），2016：245－247.

Huang Y，Zhang Y．Sichuan Environ. （黄芸，张渝．四川环境），2021，40（1）：46－52.

GB/T 27404－2008. Criterion on Quality Control of Laboratories－Chemical Testing of Food. National Standards of the People’s Republic of China（实验室质量控制规范—食品理化检测．中华人民共和国国家标准）.

Views

下载量

CSCD

Alert me when the article has been cited

提交

Tools

Publicity Resources

Study on Low-temperature Preparation of High-purity Lycopene Isomers and Their Isomerization and Degradation in Edible Oils

Determination of Paracetamol in Tablet by NMR

Preparation of Coated Cellulose Tri(4 methylbenzoate) Chiral Stationary Phases and Their Application in Enantioseparation

Related Author

No data

Related Institution

省部共建新疆特有药用资源利用国家重点实验室培育基地和中国科学院干旱区植物资源化学重点实验室

中国科学院新疆理化技术研究所

中国科学院大学

上海应用技术学院化学与环境工程学院

浙江华谱新创科技有限公司

Address：100 Xianlie Middle Road, Guangzhou Postal code：510070
Tel：020-87684776,37656606 Fax：020-87684776 Email：fxcsxb@china.com
Technical support is provided by Beijing Founder electronics co., LTD 粤ICP备12017312号-3 京公网安备11010802024621
It is recommended to read the content of this site in Chrome&IE9+. Please switch to extreme mode in browser 360.
Cookies We use cookies to help provide and enhance our service and tailor content. By continuing, you agree to the use of cookies.

⁰