Qualitative Analysis of Volatile Components in e-Liquids by Liquid-Liquid Extraction/Gas Chromatography-Mass Spectrometry and Automated Deconvolution-Kováts Retention Index Method

SHI Hong-fei; XU Bo-peng; XU Cheng-xin; QUAN Yang-ke; ZHOU Xiu-qi; YING Geng-di

doi:10.12452/j.fxcsxb.23111501

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Qualitative Analysis of Volatile Components in e-Liquids by Liquid-Liquid Extraction/Gas Chromatography-Mass Spectrometry and Automated Deconvolution-Kováts Retention Index Method

Scientific Papers | 更新时间：2024-03-13

- Qualitative Analysis of Volatile Components in e-Liquids by Liquid-Liquid Extraction/Gas Chromatography-Mass Spectrometry and Automated Deconvolution-Kováts Retention Index Method
- Journal of Instrumental Analysis Vol. 43, Issue 3, Pages: 382-392(2024)
- 作者机构：
  
  1.南京警察学院刑事科学技术学院，江苏南京 210023
  2.公安部鉴定中心，北京 100038
  3.南京市烟草公司六合分公司，江苏南京 211500
- 作者简介：
- 基金信息：
- DOI：10.12452/j.fxcsxb.23111501
  CLC： O657.7;S859.81
- Published：15 March 2024，
  
  Received：15 November 2023，
  
  Revised：29 December 2023，
- 稿件说明：
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史洪飞,徐伯芃,徐成鑫等.液液萃取/气相色谱-质谱法结合自动解卷积-Kováts保留指数法定性分析电子烟液中的挥发性成分[J].分析测试学报,2024,43(03):382-392.

SHI Hong-fei,XU Bo-peng,XU Cheng-xin,et al.Qualitative Analysis of Volatile Components in e-Liquids by Liquid-Liquid Extraction/Gas Chromatography-Mass Spectrometry and Automated Deconvolution-Kováts Retention Index Method[J].Journal of Instrumental Analysis,2024,43(03):382-392.
史洪飞,徐伯芃,徐成鑫等.液液萃取/气相色谱-质谱法结合自动解卷积-Kováts保留指数法定性分析电子烟液中的挥发性成分[J].分析测试学报,2024,43(03):382-392. DOI： 10.12452/j.fxcsxb.23111501.

SHI Hong-fei,XU Bo-peng,XU Cheng-xin,et al.Qualitative Analysis of Volatile Components in e-Liquids by Liquid-Liquid Extraction/Gas Chromatography-Mass Spectrometry and Automated Deconvolution-Kováts Retention Index Method[J].Journal of Instrumental Analysis,2024,43(03):382-392. DOI： 10.12452/j.fxcsxb.23111501.

摘要

基于液液萃取/气相色谱-质谱法结合自动解卷积-Kováts保留指数法，建立了电子烟液中挥发性成分的检测方法。对提取溶剂种类进行了优化，并依据烟液中香气成分的香气特征，分析果味和烟草味烟液的香韵构成和差异，确定不同果味烟液的特征香气成分。结果表明：①以乙醚为提取溶剂能减弱丙三醇对其他组分识别的干扰。②自动解卷积法能准确识别共流出组分和低含量组分；Kováts保留指数法提升了化合物识别的准确度。③在10种烟草味烟液中检出15种成分，以豆香、焦香香韵化合物为主；在21种果味烟液中检出80种成分，以果香、花香香韵化合物为主，确定了16类果味烟液的特征香气成分。通过随机验证实验，该方法可有效分辨不同果味类型的果味烟液和烟草味烟液。该方法样品用量少、前处理过程简单、样品分析用时短，能满足烟液中香气成分的检测需要，可为果味电子烟液的检验识别和监管提供参考。

Abstract

A method for the extraction and detection of aroma components in e-liquids by liquid-liquid extraction/gas chromatography-mass spectrometry and automatic deconvolution-Kováts retention index has been developed to provide reference for the inspection，identification，and supervision of fruit flavored e-liquids. Based on liquid-liquid extraction method，the type of extraction solvent was selected. After that the aroma composition and differences between fruity and tobacco flavored e-liquids was analyzed based on the aroma characteristics of the aroma components in the liquids to determine the characteristic aroma components of different fruity flavored e-liquids. The results showed that choosing ether as the extraction solvent weakened the interference of glycerol on the recognition of other components. Qualitative analysis of low content and co-eluting components was achieved by using the automatic deconvolution-Kováts retention index data analysis method. Fifteen components were detected in ten kinds of tobacco flavored e-liquids，with soybean and caramel aroma compounds as the main components. Eighty components were detected in twenty-one kinds of fruit flavored e-liquids，with fruity and floral aroma compounds as the main compounds，and the characteristic aroma components of sixteen types of fruit flavored e-liquids were identified. Through random validation experiments，the method can effectively differentiate between fruit flavored e-liquids and tobacco flavored e-liquids，and identify the flavor types of fruit flavored e-liquids. The detection method established in this paper has the advantages of low sample consumption，simple pre-treatment process，and short sample analysis time. It can meet the needs of detecting aroma components in e-liquids. It also provides a reference for the identification and regulation of the detection of fruity e-liquids.

关键词

液液萃取气相色谱-质谱法自动解卷积-Kováts保留指数法电子烟液特征香气成分

Keywords

liquid-liquid extractiongas chromatography-mass spectrometryautomatic deconvolution-Kováts retention index methode-liquidcharacteristic aroma component

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