Research Progress of Mercury Ion Sensors Based on Thymine Base Mismatch

王久军; 吴亚; 马博文; 张兴平

doi:doi：10.3969/j.issn.1004-4957.2020.06.018

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Research Progress of Mercury Ion Sensors Based on Thymine Base Mismatch

更新时间：2023-04-18

- Research Progress of Mercury Ion Sensors Based on Thymine Base Mismatch
- Vol. 39, Issue 6, Pages: 814-820(2020)
- 作者机构：
  
  长江大学生命科学学院
- 作者简介：
- 基金信息：
- DOI：doi：10.3969/j.issn.1004-4957.2020.06.018
  CLC：
- Published：2020
- 稿件说明：
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王久军, 吴亚, 马博文, 张兴平. Research Progress of Mercury Ion Sensors Based on Thymine Base Mismatch[J]. 2020, 39(6): 814-820.
DOI：

王久军, 吴亚, 马博文, 张兴平. Research Progress of Mercury Ion Sensors Based on Thymine Base Mismatch[J]. 2020, 39(6): 814-820. DOI： doi：10.3969/j.issn.1004-4957.2020.06.018.

摘要

基于汞离子和胸腺嘧啶的质子取代反应，可形成T-Hg(Ⅱ）-T碱基错配结构，该结构可作为新型汞离子传感器的良好识别元件。相较于传统汞离子检测方法在效率与精度上的不足，以T-Hg(Ⅱ）-T碱基错配结构为识别基团的新型汞离子传感器具有一定优势。该文综述了以T-Hg(Ⅱ）-T结构为识别基团，以不同类型报告基团为基础的汞离子传感器的研究进展与趋势，从而为后续汞离子传感器的开发提供参考。

Abstract

A T-Hg(Ⅱ）-T structure with base mismatch was formed based on the proton-substitution reaction between mercury ions and thymine

which could be used as a good recognition component for novel mercury ion sensors.Compared with the traditional detection methods

the new mercury ion sensors with T-Hg(Ⅱ）-T mismatch structure as recognizer had some advantages in efficiency and precision.In this paper

research progress and trend of this mercury ion sensors with T-Hg(Ⅱ）-T structure as recognizer based on different types of reporter groups were summarized

thus providing a reference for the development of mercury ion sensors.

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