Electrogenerated Chemiluminescence Cytosensors and Their Analytical Application

周凡; 姚政; 陈成炽; 李金花; 杨培慧

doi:doi：10.3969/j.issn.1004-4957.2019.05.015

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Electrogenerated Chemiluminescence Cytosensors and Their Analytical Application

- Electrogenerated Chemiluminescence Cytosensors and Their Analytical Application
- Vol. 38, Issue 5, Pages: 595-602(2019)
- 作者机构：
  
  1. 暨南大学化学与材料学院
  2. 暨南大学第一附属医院
- 作者简介：
- 基金信息：
- DOI：doi：10.3969/j.issn.1004-4957.2019.05.015
  CLC：
- Published：2019
- 稿件说明：
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周凡, 姚政, 陈成炽, 李金花, 杨培慧. Electrogenerated Chemiluminescence Cytosensors and Their Analytical Application[J]. 2019, 38(5): 595-602.
DOI：

周凡, 姚政, 陈成炽, 李金花, 杨培慧. Electrogenerated Chemiluminescence Cytosensors and Their Analytical Application[J]. 2019, 38(5): 595-602. DOI： doi：10.3969/j.issn.1004-4957.2019.05.015.

摘要

电致发光细胞传感器具有灵敏度高、反应可控性强、背景干扰低、分析实时、对检测对象无损等优点，近年来成为生物分析和临床诊断等领域的研究热点。该文针对电致发光细胞传感器构建以及纳米发光探针的设计介绍其在肿瘤细胞定量分析、肿瘤标志物分析、单细胞分析以及细胞功能分析等方面的应用，并对电致发光技术在细胞传感中的研究趋势进行展望。

Abstract

Electrogenerated chemiluminescence cytosensors

with the advantages of high sensitivity

strong reaction controllability

low background interference

real time analysis and nondestructiveness to the targets

have become a research hotspot in fields of biological analysis and clinical diagnosis in recent years.In this review

the discussion is focused on their applications in quantitative detection of cancer cells and tumor markers

single cell and cell function analysis through the construction of electrogenerated chemiluminescence cytosensors and the design of nanoluminescent probes.Simultaneously

the research trend for electrogenerated chemiluminescence technology in cell sensing is prospected.

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