Determination of 19 Antiseptic and Antifungal Agents Residues in Wooden Chopping Boards by Gas Chromatography－Tandem Mass Spectrometry with Surface Sampling Method

ZHANG Quan; LIU Li-ya; ZHOU Yi-bing; WU Yu-tian; LI Lei; LIN Ye; GUO Hua; ZHOU Xue; CHEN Qing-yuan

doi:10.19969/j.fxcsxb.21100802

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Determination of 19 Antiseptic and Antifungal Agents Residues in Wooden Chopping Boards by Gas Chromatography－Tandem Mass Spectrometry with Surface Sampling Method

Scientific Paper | 更新时间：2022-06-22

- Determination of 19 Antiseptic and Antifungal Agents Residues in Wooden Chopping Boards by Gas Chromatography－Tandem Mass Spectrometry with Surface Sampling Method
- Journal of Instrumental Analysis Vol. 41, Issue 5, Pages: 724-730(2022)
- 作者机构：
  
  1.贵州省疾病预防控制中心，贵州贵阳 550004
  2.贵州医科大学药学院，贵州贵阳 550025
- 作者简介：
- 基金信息：
- DOI：10.19969/j.fxcsxb.21100802
  CLC：
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张权,刘利亚,周贻兵等.表层取样法结合气相色谱－串联质谱测定竹木砧板中19种防腐防霉剂残留[J].分析测试学报,2022,41(05):724-730.

ZHANG Quan,LIU Li-ya,ZHOU Yi-bing,et al.Determination of 19 Antiseptic and Antifungal Agents Residues in Wooden Chopping Boards by Gas Chromatography－Tandem Mass Spectrometry with Surface Sampling Method[J].Journal of Instrumental Analysis,2022,41(05):724-730.
张权,刘利亚,周贻兵等.表层取样法结合气相色谱－串联质谱测定竹木砧板中19种防腐防霉剂残留[J].分析测试学报,2022,41(05):724-730. DOI： 10.19969/j.fxcsxb.21100802.

ZHANG Quan,LIU Li-ya,ZHOU Yi-bing,et al.Determination of 19 Antiseptic and Antifungal Agents Residues in Wooden Chopping Boards by Gas Chromatography－Tandem Mass Spectrometry with Surface Sampling Method[J].Journal of Instrumental Analysis,2022,41(05):724-730. DOI： 10.19969/j.fxcsxb.21100802.

摘要

建立了表层取样/气相色谱－串联质谱（GC－MS/MS）测定竹木砧板中19种防腐防霉剂残留的方法。通过表层取样法制备样品后先进行酸化，然后利用乙酸乙酯－正己烷（2∶8，体积比）混合溶剂提取，经方法优化后无需进行衍生化反应及净化操作，采用多反应监测扫描（MRM）模式检测，基质匹配溶液外标法定量。结果表明，19种组分在0.005～200.0 μg/mL范围呈良好的线性关系（,r,2,>, 0.990），检出限（LOD，,S,/,N, = 3）为0.001 ~ 0.17 mg/kg，定量下限（LOQ，,S,/,N, = 10）为0.003 ~ 0.55 mg/kg；在低、高2个不同加标水平下，19种目标物的回收率为65.8% ~ 97.2%，相对标准偏差（RSD，,n, = 6）为4.3% ~ 13%。利用该方法对市售竹木砧板和一次性筷子样品进行检测，发现非定型包装竹木砧板中存在五氯酚残留量高的风险隐患，可为相关部门提供风险预警。

Abstract

A gas chromatography－tandem mass spectrometry（GC－MS/MS） with surface sampling method was established for the determination of 19 kinds of antiseptic and antifungal agents residues in wooden chopping boards．The samples were prepared by surface sampling method，followed by acidification，and then extracted with ethyl acetate－,n,-hexane（2∶8，volume ratio） mixed solvent．The optimized method eliminated the need for derivatization reactions and purification operations．Multi-reaction monitoring scanning mode（MRM） was used for monitoring，and the external standard method with matrix-matched solution was used for quantification．Results of the optimized analysis showed that there were good linear relationships for the 19 components in the range of 0.005－200.0 μg/mL，with their correlation coefficients（,r,2,） larger than 0.990．The limits of detection（LODs，,S,/,N ,= 3） and limits of quantitation（LOQs，,S,/,N ,= 10） were in the ranges of 0.001－0.17 mg/kg and 0.003－0.55 mg/kg，respectively．The recoveries for the 19 targets at two spiked concentration levels ranged from 65.8% to 97.2%，with relative standard deviations（RSDs，,n ,= 6） of 4.3%－13%．This method was used for special food safety risk monitoring on the bamboo and wooden products related to food in Guizhou province，and the hidden risks of high pentachlorophenol residues in non-shaped packaging wooden chopping boards were discovered，which could provide an early risk warning for relevant departments．

关键词

竹木砧板表层取样防腐防霉剂气相色谱－串联质谱风险预警

Keywords

wooden chopping boardsampling in surfaceantiseptic and antifungal agentgas chromatography－tandem mass spectrometry（GC－MS/MS）risk early warning

references

Zhou M L，Wang Q，Liu D Q，Huang Y J，Li C．J. Food Saf. Qual. （周铭林，王邱，刘德群，黄雅静，李聪．食品安全质量检测学报），2020，11（13）：4201－4206.

He S J，Fan B，Li R Y，Yu J，Zhang J．Food Sci. （何淑娟，范斌，李润岩，俞婧，张京．食品科学），2011，32（16）：312－314.

Wang J，Yang S，Wang X Z，Guo Y Y，Li X J，Li K N．J. Food Saf. Qual. （王晶，杨珊，王学忠，郭莹莹，李晓娟，李康年．食品安全质量检测学报），2021，12（5）：2043－2048．

Sun K K，Liao W B，Chen Q J，Zhang Y，Li C．Guangdong Chem. Ind. （孙魁魁，廖文彬，陈启镌，张燕，李聪．广东化工），2019，46（21）：116－117.

Hu Y X，Yang X M，Wang Z，Wang C，Zhao J．Chin. J. Chromatogr. （胡彦学，杨秀敏，王志，王春，赵锦．色谱），2005，23（6）：581－584.

Zhang X N，Kang H，Peng L Z，Song D D，Jiang X，Li Y T，Chen H Y，Zeng X H．Chemosphere，2020，259：127493.

Zheng L，Liu Z T，Yan Z G，Zhang Y H，Yi X L，Zhang J，Zheng X，Zhou J L，Zhu Y．Ecotoxicol. Environ. Saf.，2017，135：216－224.

Li E C，Bolser D G，Kroll K J，Brockmeier E K，Falciani F，Denslow N D．Aquat. Toxicol.，2018，201：66－72.

GB/T 38742－2020．Bamboo Chopping Board．National Standards of the People’s Republic of China（竹砧板．中华人民共和国国家标准）.

GB 19790.1－2021．Chopsticks－PartDisposable 1：Wooden Chopsticks．National Standards of the People’s Republic of China（一次性筷子第1部分：木筷．中华人民共和国国家标准）.

GB 19790.2－2005．Chopsticks－PartDisposable 2：Bamboo Chopsticks．National Standards of the People’s Republic of China（一次性筷子第2部分：竹筷.中华人民共和国国家标准）.

Li Q，Xu J Q，Ji L．J. Food Hyg. （李启，徐峻卿，纪律．中国食品卫生杂志），2019，31（3）：236－239.

Zhou M L，He H T，Li C．Food Ind. （周铭林，何海彤，李聪．食品工业），2020，41（3）：278－281.

China National Center for Food Safety Risk Assessment．National Handbook for Risk Monitoring of Food Contamination and Harmful Factors（国家食品安全风险评估中心．2018年国家食品污染和有害因素风险监测工作手册），2018.

Ma H W，Zhang D Y，Huang X X．Leather Sci. Eng. （马贺伟，张丹云，黄新霞．皮革科学与工程），2009，19（3）：71－74.

Lan H J，Wu X M，Feng Y J，Li S Y．J. Food Hyg. （兰红军，吴雪梅，冯耀基，黎少映．中国食品卫生杂志），2019，31（3）：231－236.

Bao M Z，Chen Y H，Li N，Wu Z X，He S．J. Northwest For. Univ. （鲍敏振，陈玉和，李能，吴再兴，何盛．西北林学院学报），2019，34（6）：197－201，239.

Zhang Z R，Zhang L Y，Wang Y J，Liu Y T，Xin Z J．J. Food Hyg. （张志荣，张来颖，王玉江，刘裕婷，信振江．中国食品卫生杂志），2019，31（3）：226－230.

Jiang K L，Hu B，Wu X Q，Xie Y J，Li T M，Fan C L，Wang M L，Wang W W，Chen H．J. Instrum. Anal. 蒋康丽，扈斌，吴兴强，谢瑜杰，李铁梅，范春林，王明林，王雯雯，陈辉．分析测试学报），2021，40（9）：1257－1270.

Yang C X，Zhang K，Zhong H Y．Mod. Prev. Med.（杨长晓，张坤，钟海洋．现代预防医学），2021，48（1）：144－147.

Council of Europe. Resolution AP（2004） 2 on Cork Stoppers and Other Cork Materials and Articles Intended to Come into Contact with Foodstuffs．［2021－07－06］．https：//search.coe.int/cm/Pages/result_details.aspx？ObjectID=09000016804e47f6https://search.coe.int/cm/Pages/result_details.aspx?ObjectID=09000016804e47f6.

Yuan Y，Zhou Y，Xiong L，Song Y C．Mod. Prev. Med.（袁娅，周颖，熊丽，宋迎春．现代预防医学），2021，48（14）：2538－2541.

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