
浏览全部资源
扫码关注微信
1.天津中医药大学 中药制药工程学院,天津 301617
2.现代中医药海河实验室,天津 301617
3.天津市 中药智能制药与绿色制药重点实验室,天津 301617
Received:30 May 2026,
Revised:2026-06-24,
Accepted:04 August 2026,
Online First:14 August 2026,
Published:15 October 2026
移动端阅览
沙鑫,刘嘉诚,朱贝贝,李文龙.基于碳足迹核算的中药制粒工艺绿色化评价方法构建及优化路径[J].分析测试学报,2026,45(10):2269-2278.
SHA Xin,LIU Jia-cheng,ZHU Bei-bei,LI Wen-long.Construction and Optimization Path of Greenness Evaluation Method for Traditional Chinese Medicine Granulation Processes Based on Carbon Footprint Accounting[J].Journal of Instrumental Analysis,2026,45(10):2269-2278.
沙鑫,刘嘉诚,朱贝贝,李文龙.基于碳足迹核算的中药制粒工艺绿色化评价方法构建及优化路径[J].分析测试学报,2026,45(10):2269-2278. DOI: 10.12452/j.fxcsxb.26053001.
SHA Xin,LIU Jia-cheng,ZHU Bei-bei,LI Wen-long.Construction and Optimization Path of Greenness Evaluation Method for Traditional Chinese Medicine Granulation Processes Based on Carbon Footprint Accounting[J].Journal of Instrumental Analysis,2026,45(10):2269-2278. DOI: 10.12452/j.fxcsxb.26053001.
在“双碳”目标和制造业绿色低碳转型背景下,中药制粒工艺亟需建立可量化、可比较的绿色化评价方法。然而,现有评价多侧重单一能耗、收率或工艺类型比较,缺乏统一的系统边界、功能单位和质量约束,难以客观反映不同制粒工艺的绿色化程度。基于此,该文以碳足迹核算理念为基础,“从浸膏或浓缩液到合格颗粒”为过程边界,“单位合格颗粒输出”为功能单位,梳理中药制粒过程中的关键排放来源,比较不同制粒及干燥成型工艺路线的绿色化特征,并提出中药制粒绿色化程度评价公式。同时,以喷雾干燥和流化床制粒文献案例对该公式的应用方式进行了示例说明,表明其可将不同工艺中的能源消耗、物料投入、过程损失、辅助系统运行和质量偏差统一折算至单位合格颗粒产出。该方法可为中药制粒工艺低碳评价、路线筛选和智能化优化提供参考。
Against the background of China’s“dual carbon”goals and the green and low-carbon transformation of the manufacturing industry,traditional Chinese medicine granulation processes urgently require a quantifiable and comparable greenness evaluation method. However,existing evaluation methods mainly focus on single indicators such as energy consumption,yield,or process type and lack unified system boundaries,functional units,and quality constraints,making it difficult to objectively reflect the greenness of different granulation processes. Therefore,based on the concept of carbon footprint accounting,this study defines“from extract or concentrated liquid to qualified granules”as the process boundary and“unit output of qualified granules”as the functional unit. The key emission sources in traditional Chinese medicine granulation are summarized,the greenness characteristics of different granulation and drying-forming process routes are compared,and a formula for evaluating the greenness of traditional Chinese medicine granulation processes is proposed. The application of this formula is illustrated with literature cases of spray drying and fluidized bed granulation,showing that it can uniformly convert energy consumption,material input,process loss,auxiliary system operation,and quality deviation in different processes into unit qualified particle output. This method can provide a reference for the low-carbon evaluation,route screening,and intelligent optimization of traditional Chinese medicine granulation processes.
Ministry of Ecology and Environment of the People's Republic of China . The Information Office of the State Council has released the “China's Actions on Carbon Peak and Carbon Neutrality” white paper (with full text attached)(中华人民共和国生态环境部 . 国务院新闻办公室发布《碳达峰碳中和的中国行动》白皮书(附全文)) . [ 2026-05-29 ]. https://www.mee.gov.cn/ywgz/ydqhbh/qhbhlf/202511/t20251108_1132414.shtml https://www.mee.gov.cn/ywgz/ydqhbh/qhbhlf/202511/t20251108_1132414.shtml .
Liu X J , Qi Y R , Wu Z F , Wang X C , Zhu W T , Xu H H , Li Y H , Yang M . Chin . Tradit. Herb. Drugs (刘杏健,齐娅汝,伍振峰,王学成,朱雯婷,徐焕华,李远辉,杨明. 中草药), 2025 , 56 ( 19 ): 7211 - 7221 .
Dong Z G , Zhou R , He J F , Liu W L , Chen Y Q , Wang H C , Li C R , Yan H Y . Chin . Tradit. Herb. Drugs (董治国,周容,何金凤,刘文龙,陈雨晴,王虎传,李传润,颜海洋. 中草药), 2024 , 55 ( 12 ): 4225 - 4234 .
Kong L H , Ma Y N , Zhang A J , Zhang D L , Li X F , Li F , Shi L . Lishizhen Med . Mater. Med. Res. (孔令辉,马艳妮,张爱均,张代亮,李学芬,李峰,史磊. 时珍国医国药), 2024 , 35 ( 12 ): 2842 - 2846 .
Li Z , Sun C Y , Xiao Z J , Xue X , Zhong Z J , Guan Z Y , Wu W T , Li Q , Guan Y M , Jin Z J , Ming L S , Zhu W F . Chin . Tradit. Herb. Drugs (李哲,孙彩云,萧子健,薛晓,钟志坚,关志宇,吴文婷,李琼,管咏梅,金正吉,明良山,朱卫丰. 中草药), 2025 , 56 ( 18 ): 6493 - 6505 .
Patra C N , Pandit H K , Singh S P , Devi M V . AAPS PharmSciTech , 2008 , 9 ( 1 ): 100 - 104 .
ISO 14067 - 2018 . Greenhouse Gases-Carbon Footprint of Products-Requirements and Guidelines for Quantification. International Organization for Standardization(温室气体-产品碳足迹-量化要求及指南. 国际标准化组) .
World Resources Institute , World Business Council for Sustainable Development . Product Life Cycle Accounting and Reporting Standard (世界资源研究所,世界可持续发展工商理事会 . 产品生命周期会计和报告标准) . [ 2026-05-29 ]. https://ghgprotocol.org/sites/default/files/standards/Product-Life-Cycle-Accounting-Reporting-Standard_041613.pdf https://ghgprotocol.org/sites/default/files/standards/Product-Life-Cycle-Accounting-Reporting-Standard_041613.pdf .
Wang M , Mu H , Peng L , Tan C , Chen Y , Sheng J , Tian Y , Zhao C . J. Food Eng. , 2024 , 376 : 112083 .
Qi F Y , Li W J , Zhao X Q , Cao J J , Qiao Y J , Xu B . China J. Chin. Mater. Med. (齐飞宇,李文静,赵晓庆,曹君杰,乔延江,徐冰. 中国中药杂志), 2023 , 48 ( 12 ): 3169 - 3179 .
Ci Z M , Ma H Y , Li Z , Yang M , Wang X C , Wu Z F , Zhang D K . Chin . Tradit. Herb. Drugs (慈志敏,马鸿雁,李正,杨明,王学成,伍振峰,张定堃. 中草药), 2026 , 57 ( 3 ): 789 - 798 .
Chen X H , Cao L Y , Wang Y J , He Z Q , Cao W Z . Bull. Chin. Acad. Sci. (陈晓红,曹廖滢,汪阳洁,何竺虔,曹文治. 中国科学院院刊), 2025 , 40 ( 10 ): 1777 - 1791 .
Yan Z P , Li X X . Chin . Tradit. Pat. Med. (闫治攀,李喜香. 中成药), 2026 , 48 ( 2 ): 593 - 602 .
Liang J J , Zhang Y , Pan H M , Rao X Y , Liu W , Luo X J , He Y . Chin . J. New Drugs (梁钧杰,张尧,潘浩敏,饶小勇,刘微,罗晓健,何雁. 中国新药杂志), 2024 , 33 ( 8 ): 774 - 784 .
Zhong Y H , Hui Y Y , Tian W L , Yin Q Q , Zhang Y , Li J W , Deng X P . J . Tianjin Tradit. Chin. Med. Univ. (钟雨虹,惠玉玉,田文丽,殷倩倩,张瀛,李佳玮,邓秀平. 天津中医药大学学报), 2024 , 43 ( 8 ): 745 - 751 .
Bao Y , Tian L J , Zhang D K , Xie Y L , Zhou J W , Li X , Ma H Y . J. Chin. Med. Mater. (鲍洋,田琳洁,张定堃,谢易伶,周靖惟,李雪,马鸿雁. 中药材), 2025 , 48 ( 1 ): 253 - 260 .
Fu H , Teng K X , Xie X Y , Zhao J , Qu H B . Chin. Tradit. Herb. Drugs (傅豪,腾凯旋,谢欣媛,赵洁,瞿海斌. 中草药), 2021 , 52 ( 2 ): 396 - 403 .
Zhan J J , Wu Z F , Shang Y , Wang X C , Yue P F , Wang Y Q , Zang Z Z , Yang M . Chin . Tradit. Herb. Drugs (詹娟娟,伍振峰,尚悦,王学成,岳鹏飞,王雅琪,臧振中,杨明. 中草药), 2017 , 48 ( 12 ): 2365 - 2370 .
Eremin V A , Blynskaya E V , Alekseev K V , Tishkov S V , Minaev S V . Pharm. Chem. J. , 2024 , 58 ( 9 ): 1438 - 1447 .
Shui L S , Li Y , Liu L , Liu J Q , Guo Y X . Chin. J. Pharm. (水林森,李扬,刘鸾,刘剑桥,郭永学. 中国医药工业杂志), 2021 , 52 ( 10 ): 1347 - 1355 .
Diao Y L , Ban J F , Xie Q C , Lin M M , Wang B , Lü Z F , Chen Y Z . Chin . Tradit. Pat. Med. (刁艳玲,班俊峰,谢清春,林敏玫,王博,吕竹芬,陈燕忠. 中成药), 2017 , 39 ( 2 ): 414 - 417 .
Zeng J , Huang T , Feng L L , Xue M , Chen J X , Du R F , Fen Y . Chin . J. New Drugs (曾佳,黄婷,俸灵林,薛嫚,陈建兴,杜若飞,冯怡. 中国新药杂志), 2019 , 28 ( 11 ): 1330 - 1342 .
Ahmed J , Thomas L , Mulla M Z , Attar H A , Maniruzzaman M . Food Res. Int. , 2023 , 165 : 112497 .
Zhang Q L , Luo Y H , Xu G H , Yang H . Mod. Chin. Med. (张青铃,罗友华,许光辉,杨辉. 中国现代中药), 2020 , 22 ( 5 ): 827 - 834 .
Zhang S , Gong G , Wang H , Chen S , Wang J , Qi J . Sustainable Mater . Technol. , 2025 , 43 : e01250 .
Wan Q , Gao H , Qi Y R , Qiu X R , Li Y S , Yang M , Li Y H , Wu Z F . Chin . Tradit. Herb. Drugs (万琴,高欢,齐娅汝,邱勋荣,李玉珊,杨明,李远辉,伍振峰. 中草药), 2023 , 54 ( 23 ): 7884 - 7894 .
Xie P , Wen R H , Wei H F , Shen J H , Hao C L , Chen L H . Chin . Tradit. Pat. Med. (谢平,温仁华,魏海峰,沈金海,郝春莉,陈良华. 中成药), 2024 , 46 ( 2 ): 556 - 561 .
Gomes J V P , Oliveira L A D , Pereira S M S , Conceiça˜o A R , Anunciaça˜o P C , Souza E C G , Perrone I T , Junqueira M S , Sant'ana H M P , Lucia C M D . Food Chem. , 2021 , 345 : 128772 .
Radisavljević A , Milutinović M , Branković S D , Uskoković P . Stojanović M R . Hemijska Industrija , 2021 , 75 ( 6 ): 353 - 363 .
Chen S , Fan L , Chen X , Guo Z , Zhang B . LWT , 2025 , 223 : 117778 .
Borkhataria C , Chauhan H , Mistry B , Kalaria M , Katbamana R , Patel K . Int. J. Chem. Eng. , 2024 , 2024 ( 1 ): 8734695 .
Wahab W , Alshamsi R , Alharsousi B , Alnuaimi M , Alhammadi Z , Zaitone B A . Pharmaceutics , 2025 , 17 ( 12 ): 1605 .
Lü Z Y , Zhang Y , Yang S W , Wang X C , Chen J , Yang Y W . Chin . Tradit. Herb. Drugs (吕志阳,张玉,杨苏皖,王希晨,陈静,杨雨微. 中草药), 2025 , 56 ( 13 ): 4634 - 4642 .
Wang J , Wu P , Dhital S , Yu A , Chen X D . Foods , 2025 , 14 ( 10 ): 1817 .
Yang M , Li L , Zhu X , Liang L , Chen J , Cao W , Liu W , Duan X , Ren G , Liu Z . J. Food Sci. , 2024 , 89 ( 6 ): 3276 - 3289 .
Li X , Yi J , He J , Dong J , Duan X . LWT , 2024 , 192 : 115740 .
Sha X , Chang H , Song W , Yu H S , Li Z , Li W L . J. Instrum. Anal. (沙鑫,常淏,宋纹,余河水,李正,李文龙. 分析测试学报), 2026 , 45 ( 6 ): 1212 - 1220 .
Fang G , Jia C , Guan Z , Li F , Li Z , Li W . AAPS PharmSciTech , 2026 , 27 ( 3 ): 115 .
Teng K , Fu H , Wu G , Gong P , Xie Y , Zhou P , Gong X , Qu H . AAPS PharmSciTech , 2023 , 24 : 210 .
Sha X , Chang H , Song W , Yu H S , Li Z , Li W L . J. Instrum. Anal. (沙鑫,常淏,宋纹,余河水,李正,李文龙. 分析测试学报), 2026 , 45 ( 6 ): 1174 - 1187 .
Zhang Z P , Zhang L L , Shi W T , Wang S F , Chen W M , Wang M , Sun D M . Chin . Tradit. Herb. Drugs (张志鹏,张兰兰,施文婷,王寿富,陈伟媚,汪梅,孙冬梅. 中草药), 2023 , 54 ( 22 ): 7429 - 7435 .
Xie Q T , Li H Y , Zhao X J , He H , Guo Y F , Liu Y , Ma S W , Wu Z S . Chin . Tradit. Herb. Drugs (谢洽桐,李海洋,赵小军,何晗,郭玉凤,刘洋,马世威,吴志生. 中草药), 2026 , 57 ( 1 ): 53 - 63 .
Zhou G , Chang H , Fang G , Cai X , Rong Z , Li W . Drug Dev. Ind. Pharm. , 2026 , 52 ( 4 ): 735 - 749 .
Avila C R , Ferré J , Oliveira R R , Juan A , Sinclair W E , Mahdi F M , Hassanpour A , Hunter T N , Bourne R A , Muller F L . Pharm. Res. , 2020 , 37 ( 5 ): 84 .
Yang G D , Ao G , Chen Y , Huang Y F , Chen S , Li D X , Zhang W L , Wang T T , Zhang G S . China J. Chin. Mater. Med. (杨广迪,敖歌,陈杨,黄玉芳,陈殊,李东勲,张文锍,王甜甜,张国松. 中国中药杂志), 2025 , 50 ( 6 ): 1484 - 1495 .
Chen P , Ansari M J , Bokov D , Suksatan W , Rahman M L , Sarjadi M S . Arabian J. Chem. , 2022 , 15 ( 2 ): 103598 .
0
Views
21
下载量
0
CSCD
Publicity Resources
Related Articles
Related Author
Related Institution
京公网安备11010802024621