XU Tao,JIN Lei,XIA Peng-zhi.Advances in Analyzing Techniques for NAD Levels within Biological Cells[J].Journal of Instrumental Analysis,2024,43(07):1076-1085.
XU Tao,JIN Lei,XIA Peng-zhi.Advances in Analyzing Techniques for NAD Levels within Biological Cells[J].Journal of Instrumental Analysis,2024,43(07):1076-1085. DOI: 10.12452/j.fxcsxb.24030401.
Advances in Analyzing Techniques for NAD Levels within Biological Cells
Nicotinamide adenine dinucleotide(NAD)is a key accessory molecule prevalent in all living cells and plays an important role in cellular metabolism. NAD directly controls intracellular energy metabolism,participates in DNA damage repair,regulates intracellular calcium ion concentration,and other important life processes,and plays a critical role in the metabolic reactions of cells. The study of NAD level in biological cells has been one of the research hotspots in life science research in the last 20 years. In this paper,we summarize the research progress of NAD level detection methods in biological cells from the perspectives of structural properties and synthesis pathways of NAD,introduce the principles,advantages and disadvantages,and the scope of application of various methods,and look forward to the development trend of the methods,in order to provide a good guidance for the related research.
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