ZHANG Wen-ting,WANG Kai-jun,LU Ya-mei,YANG Wu-ye,XIONG Yin-ran,WU Qiong,DU Yi-ping.Near Infrared and Ultraviolet-Visible Dual-spectrum Online Monitoring of the Extraction Process of Chinese Medicine Dracocephalum Tanguticum Maxim[J].Journal of Instrumental Analysis,2024,43(05):746-754.
ZHANG Wen-ting,WANG Kai-jun,LU Ya-mei,YANG Wu-ye,XIONG Yin-ran,WU Qiong,DU Yi-ping.Near Infrared and Ultraviolet-Visible Dual-spectrum Online Monitoring of the Extraction Process of Chinese Medicine Dracocephalum Tanguticum Maxim[J].Journal of Instrumental Analysis,2024,43(05):746-754. DOI: 10.12452/j.fxcsxb.23120845.
Near Infrared and Ultraviolet-Visible Dual-spectrum Online Monitoring of the Extraction Process of Chinese Medicine Dracocephalum Tanguticum Maxim
An online monitoring system of near infrared spectrum(NIR) and ultraviolet-visible spectroscopy(UV-Vis) is constructed using small optical fiber spectrometers,and the spectra are online collected with the system. After a spectrum collection,the sample is sent back into the extraction container to avoid the loss of the extraction liquid,and the pipeline is cleaned with the backward flow to prevent the pipeline from clogging. The extraction process is monitored by the dual-spectrum system to improve the acquisition of spectral information. Sampling error profile analysis(SEPA) and stability competitive adaptive reweighted sampling(SCARS) and other chemometric methods are used for the spectral process and model establishment. The analytical performances of NIR spectroscopy,UV-Vis spectroscopy and dual-spectrum fusion models are compared. The results show that the NIR spectral model of luteolin and the UV-Vis model of chlorogenic acid are better. The predicted root-mean-square error(RMSEP) of luteolin model is 0.010 7 μg·mL
-1
,and that of chlorogenic acid model is 0.029 5 mg·mL
-1
. The system developed in this study is simple,rapid and has high model accuracy,which provides a new strategy for online monitoring of Chinese medicine extraction.
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