ZHU Yi-ting,LI Zhi-yao,XIE Mao-mei,et al.Research Advances in Surface-enhanced Raman Spectroscopy Technology in the Analysis of Bacterial Physiological Active Factors and Metabolites[J].Journal of Instrumental Analysis,2024,43(01):138-146.
ZHU Yi-ting,LI Zhi-yao,XIE Mao-mei,et al.Research Advances in Surface-enhanced Raman Spectroscopy Technology in the Analysis of Bacterial Physiological Active Factors and Metabolites[J].Journal of Instrumental Analysis,2024,43(01):138-146. DOI: 10.12452/j.fxcsxb.23091401.
Research Advances in Surface-enhanced Raman Spectroscopy Technology in the Analysis of Bacterial Physiological Active Factors and Metabolites
Surface-enhanced Raman scattering(SERS) technology,as a highly sensitive and high-resolution analytical method,has shown broad application prospects in the field of bacterial research. Not only bacterial content can be detected at extremely low concentration levels,but its microscopic resolution can penetrate deep into the interior of bacteria,providing an opportunity for a profound understanding of bacterial composition and metabolic behavior. Without the need for complex pre-treatment steps,SERS technology can simultaneously monitor multiple bacterial metabolites,improving the efficiency and accuracy of analysis. These characteristics make SERS technology a powerful tool for comprehensively understanding the physiological activity and metabolites of bacteria. This article first introduces the concept,enhancement mechanism,and enhancement substrate materials of SERS technology,and then focuses on the research progress of SERS technology in the analysis of bacterial physiological active factors and metabolites. Finally,while pointing out its limitations,it also looks forward to future development trends.
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