Rapid Analysis of Chemical Constituents in Eurycoma longifolia Jack by Ultra performance Liquid Chromatography-Quadrupole Time of flight Mass Spectrometry
|更新时间:2023-04-18
|
Rapid Analysis of Chemical Constituents in Eurycoma longifolia Jack by Ultra performance Liquid Chromatography-Quadrupole Time of flight Mass Spectrometry
Vol. 39, Issue 4, Pages: 449-460(2020)
作者机构:
1. 福建省微生物研究所
2. 福建省新药(微生物)筛选重点实验室
作者简介:
基金信息:
DOI:
CLC:
扫 描 看 全 文
Rapid Analysis of Chemical Constituents in Eurycoma longifolia Jack by Ultra performance Liquid Chromatography-Quadrupole Time of flight Mass Spectrometry. [J]. 39(4):449-460(2020)
DOI:
Rapid Analysis of Chemical Constituents in Eurycoma longifolia Jack by Ultra performance Liquid Chromatography-Quadrupole Time of flight Mass Spectrometry. [J]. 39(4):449-460(2020)DOI:
Rapid Analysis of Chemical Constituents in Eurycoma longifolia Jack by Ultra performance Liquid Chromatography-Quadrupole Time of flight Mass Spectrometry
An ultra performance liquid chromatography-quadrupole time of flight mass spectrometric(UPLC-Q-TOF-MS) method was established for the identification of chemical constituents in the extract of Eurycoma longifolia Jack.The sample was separated on an Agilent Eclipse Plus-C18 RRHD(2.1 mm×100 mm,1.8 μm) column with acetonitrile and 0.1% formic acid water as mobile phases by gradient elution.The data were collected with electrospray ionization in positive mode.According to the contrast of the reference standards and the accurate masses of molecules,a total of 49 compounds in Eurycoma longifolia Jack extract were identified,including 29 quassinoid diterpenoids,4β-carboline alkaloids,12 canthin-6-one alkaloids,3 biphenyl-neolignans and 1 squalene triterpene.The method was accurate,reliable and efficient,and could comprehensively reflect the chemical constituents of Eurycoma longifolia Jack,and provided a reference for further elucidating its pharmacological basis and quality controll.
Rapid Identification of Constituents in Keke Tablets by High-performance Liquid Chromatography-Quadrupole Time-of-flight Mass Spectrometry
Research Progress on Untargeted Screening of Compounds in Food Contact Materials
Online Detection of Clear Point in Esterification Process of Polyester Production Based on Raman Spectroscopy
Preparation and Uncertainty Valuation of Naringenin Certified Reference Material
Confirmation of the Structure of a New Sildenafil Analogue
Related Author
No data
Related Institution
Zhongshan Zhongzhi Pharmaceutical Group Co.,Ltd.
Guangdong Provincial Engineering Research Center for Quality and Safety of Traditional Chinese Medicine,Guangdong Provincial Key Laboratory of Chemical Measurement and Emergency Test Technology, Institute of Analysis,Guangdong Academy of Sciences(China National Analytical Center,)
National Reference Laboratory for Food Contact Material(Guangdong),Guangzhou Customs District Technology Center