A novel high performance liquid chromatography(HPLC) with dispersive liquid-liquid microextraction based on vortex assisted solidification of floating deep eutectic solvent(VA-DLLME-SFDES) was established for the determination of triclosan and triclocarban in water samples.Six hydrophobic deep eutectic solvents(DESs) were newly synthesized,which physical and chemical constants such as density,melting point and octanol-water partition coefficient(KOW) were determined.One of the low density DES with suitable freezing point was selected as the micro-extractant.After vortex assisted extraction and freezing,the extractant was solidified and attached to the inner wall of the centrifuge tube.After removing the aqueous phase,the DES was melted and centrifuged in room temperature,and followed by HPLC analysis.The optimum extraction conditions were as follows：DES prepared with menthol-1 dodecanol(1∶2,molar ratio) as extraction solvent,volume of extraction solvent：70 μL,pH of water sample：5.0,vortex time：1 min.Under the optimum conditions,there were good linearities for triclosan and triclocarban in the concentration ranges of 0.59-100 μg/L and 0.26-100 μg/L,respectively,with their correlation coefficients(r2) of 0.999 8 and limits of detection(S/N=3) of 0.08-0.18 μg/L.The enrichment factors for the analytes varied from 141 to 148.Meanwhile,the recoveries were in the range of 86.0%-115% with intra-precision(n=6) and inter-precision(n=6) not more than 5.4%.The method is simple,rapid and easy in collecting the extraction phase,and it is suitable for the determination of triclosan and triclocarban in water.