Plasma metals(gold,silver) nanostructures are widely used in surface enhanced Raman scattering(SERS) and wearable stress sensing fields due to their unique physical and chemical properties.Among them,SERS is a kind of detection technology using plasma metal nanomaterials to enhance Raman scattering singal.It has high sensitivity and speciticity,and has been widely used in biomedical analysis,environmental monitoring,food and drug detection and other fields.With the rapid development of electronic detection technique and flexible electronic materials,flexible wearable sensing technique has also been developed rapidly,and a large number of research achievements have been obtained.SERS detection technique mainly relies on substrate materials of plasma metals,and wearable sensing elements based on Plasma metal nanostructures have extremely high sensitivity to human micro stress and micro strain.As SERS reinforced substrate materials and wearable stress sensor materials contain interoperability,application of SERS plasma metal nano substrate in flexible wearable detection is one of the application fields which is relatively new but not yet deeply studied.Therefore,the material composition classification of plasma metal sol nanostructures and their applications in SERS and wearable stress sensing are reviewed in this paper.Moreover,effects of these nanostructures on the sensitivity,repeatability and stability of SERS sensing and wearable stress sensing has been investigated.The development trend of precious metal colloidal nanostructures in SERS sensing and flexible wearable sensing elements is also forecasted.