Temperature Induced Ionic Liquids Dispersive Liquid-Liquid Microextraction/Ultrahigh Pressure Liquid Chromatography Determination of Trace Tetracyclines Antibiotics in Environmental Water
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Temperature Induced Ionic Liquids Dispersive Liquid-Liquid Microextraction/Ultrahigh Pressure Liquid Chromatography Determination of Trace Tetracyclines Antibiotics in Environmental Water
Vol. 30, Issue 3, Pages: 259-263(2011)
作者机构:
1. 内蒙古大学化学化工学院
2. 中国科学院生态环境研究中心
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Temperature Induced Ionic Liquids Dispersive Liquid-Liquid Microextraction/Ultrahigh Pressure Liquid Chromatography Determination of Trace Tetracyclines Antibiotics in Environmental Water. [J]. 30(3):259-263(2011)
DOI:
Temperature Induced Ionic Liquids Dispersive Liquid-Liquid Microextraction/Ultrahigh Pressure Liquid Chromatography Determination of Trace Tetracyclines Antibiotics in Environmental Water. [J]. 30(3):259-263(2011)DOI:
Temperature Induced Ionic Liquids Dispersive Liquid-Liquid Microextraction/Ultrahigh Pressure Liquid Chromatography Determination of Trace Tetracyclines Antibiotics in Environmental Water
A confirmatory method using ultrahigh pressure liquid chromatography(UPLC) coupled with tunable ultraviolet detector(TUV) was developed for the determination of trace levels of tetracyclines,including chlortetracycline(CTC),doxycycline(DC),4 epitetracycline(ETC),4 epichlortetracycline(ECTC),4 epianhydrotetracycline(EATC),oxytetracycline(OTC),tetracycline(TC) and anhydrotetracycline(ATC),in environmental water samples.The rare earth metal La ions were used as chelating agent to form a hydrophobic complex compound with TCs.Temperature induced ionic liquids dispersive liquid-liquid microextraction(DLLME)was used to concentrate the target compound.Effects of experimental conditions,including the kinds and amounts of ionic liquids,heating temperature,time of complexation and extraction,concentration of Triton X 114 and pH value,on extraction efficiencies were investigated.Under the optimum conditions,the calibration curves were linear in the range of 10-200 μg?L-1 for ETC,TC,DC and ATC,and 01-200 μg?L-1 for ECTC,CTC and EATC,and 10-200 μg?L-1 for OTC,respectively,with correlation coefficients(r2) more than 099.The limits of detection(LODs) ranged from 003 μg?L-1 to 579 μg?L-1,and the limits of quantitation(LOQs) were in the range of 009-191 μg?L-1.The spiked recoveries of eight target compounds in river water,fishpond water and leaching water of the pig farm soil were achieved in the range of 63%-96%,59%-94% and 55%-86%,respectively.The investigation results of environmental water samples in Beijing showed that 214 μg?L-1CTC and 009 μg?L-1 ECTC were detected in waste water from hoggery and no target compounds were found in the river water and fishpond water samples.As a result,this method could be applied in the rapid and convenient determination of eight tetracycline antibiotics in real environmental water samples.
Analysis of Tetrabutylphosphorus and Tetrabutylammonium by Hydrophilic Interaction Chromatography with Indirect Ultraviolet Detection Using Ionic Liquids as Mobile Phase Additives
Analysis of Pyridinium Ionic Liquid Cations by Ion Chromatography with Direct Conductivity Detection
Electrochemical Behavior and Determination of Bisphenol A on the Gold Nanoparticles-Ionic Liquid Modified Electrode
Simultaneous Determination of Pyridinium and Imidazolium Ionic Liquid Cations by Ion-pair Chromatography
Effects of Ionic Liquids as Mobile Phase Additives on the Separation of Capsaicin-type Alkaloids by HPLC