A nano-Fe2O3 modified glassy carbon electrode（Fe2O3/GCE) was fabricated and the stripping voltammetry behavior of cadmium ion on this modified electrode was studied.The results indicated that the presence of Fe2O3 nanoparticles can effectively enhance the stripping voltammetric response of cadmium ion.In pH 6.0 phosphate buffer solution,cadmium ion was adsorbed onto the surface of Fe2O3 nanoparticles effectively and then reduced at -1.0 V.During the positive potential sweep,the reduced cadmium was oxidized again and an obvious stripping oxidation peak was observed at about -0.85 V.The current of the stripping peak was increased with the increase of cadmium ion concentration.Based on this,a novel method for the determination of cadmium ion was developed based on nano Fe2O3 modified electrode（Fe2O3/GCE).The experimental conditions were optimized.Under the optimum conditions（pH value：6.0,accumulation time：350 s,accumulation potential：-1.0 V),the current response of cadmium ion increased linearly with concentration of cadmium ion in the ranges of 6.0×10-10-1.0×10-8 mol/L and 1.0×10-8- 1.0×10-5mol/L,with a detection limit of 1.0×10-10 mol/L at 3σ.Some common metal ions and cations had no obvious effects on the determination of cadmium ion.This method was used in the determination of cadmium ion in real water samples with satisfactory recovery.