A method based on high performance liquid chromatography tandem mass spectrometry（HPLC-MS/MS） with accelerated solvent extraction（ASE） was developed for the quantitative detection of perfluorooctanoic acid（PFOA） in plastic component of the household appliances.The sample was extracted with accelerated solvent extraction using methanol as extraction solvent.The extract were purified and enriched on a C18 column by solid phase extraction（SPE） column.The target compound was separated on a C18 column using methanol-water as mobile phase by gradient elution，and detected by MS with electrospray ionization（ESI） under multiple reaction monitoring(MRM) mode.The calibration curve was linear in the range of 0.5-100.0 μg/L with a correlation coefficient（r2） of 0.998 9.The recoveries for PFOA were in the range of 93%-107% with relative standard deviations of 2.9%-7.6%.The detection limit（S/N=3） was 0.5 μg/kg.The method is easy-handling，time-saving and sensitive, and is suitable for the determination of PFOA in plastic component of household appliances.