In this paper,based on the obvious enhancing effect of sodium bromide on the NaIO4-H2O2-metoclopramide weak chemiluminescence(CL) reaction system under acidic conditions and combined with the flow injection analysis，a new method for the determination of metoclopramide was proposed.Under the optimum conditions,the relative CL intensities were proportional to the metoclopramide concentrations in the range of 1.00×10-9-1.20×10-6 g/mL with a detection limit of 3.5×10-10 g/mL.The relative standard deviation(ρ=1.00×10-7g/mL,n=11) was 2.5%.The proposed method was successfully applied in the determination of metoclopramide tablets and spiked urine sample with recoveries of 96%-100%.The results were in agreement with that of the standard method