Highly Selective Analysis of Proteins Based on Targetable Peptide Probes

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Highly Selective Analysis of Proteins Based on Targetable Peptide Probes

- Highly Selective Analysis of Proteins Based on Targetable Peptide Probes
- Vol. 31, Issue 9, Pages: 1184-1190(2012)
- 作者机构：
  
  中国科学院化学研究所中国科学院活体分析化学重点实验室
- 作者简介：
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Highly Selective Analysis of Proteins Based on Targetable Peptide Probes. [J]. 31(9):1184-1190(2012)
DOI：

Highly Selective Analysis of Proteins Based on Targetable Peptide Probes. [J]. 31(9):1184-1190(2012) DOI：

摘要

高选择性、高灵敏度的蛋白质分析检测方法是复杂生命体系研究的有力工具，能为疾病的发现、治疗以及分子机制研究提供新的、有价值的思路和手段。该文围绕蛋白质与多肽的分子识别，针对疾病相关多肽、蛋白质的分离、分析与检测新方法，综述了近几年取得的研究进展，可为复杂生命体系中生理活性分子的结构与功能研究提供借鉴。

Abstract

The development of highly selective methods for the analysis of proteins in biosystems is crucial for studying their structures and biological functions.These methods will offer new opportunities to explore complex disease-related biological processes at the molecular level both in vitro and in vivo.Herein，recent progress in highly selective analysis of proteins is summarized focusing on the molecular-probe based approach，colorimetric detection as well as microfluidic technique.

关键词

蛋白质多肽探针分子识别高选择性分析

Keywords

proteinpeptide probemolecular recognitionhighly selective analysis

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Key Laboratory of Medical Optical Instrument and Equipment of Ministry of Education， School of Optical－Electrical and Computer Engineering， University of Shanghai for Science and Technology

Photonics Advanced Research Center， Osaka University， Osaka　565－

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