An ion chromatographic method with post-column deriviation and UV detection for the determination of iodate and bromate in cosmetics was developed and validated.The sample was purified with a guard-column IonPac AG11-HC(50 mm×4 mm),and separated on an analytical column IonPac AS11-HC(250 mm×4 mm) using KOH as an eluent with a self-regeneration suppressor.NaNO2 and KBr were used as the post-column deriviation solution.The analyte was quantitatively analysed by external standard and detected with a DAD detector.The results showed that the calibration curves were linear in the range of 2.0-1 000 mg/kg with correlation coefficients not less than 0.999 8.The spiked recoveries were in the range of 84%-99% with relative standard deviations(RSDs,n=3) less than 2%.With advantages of simplicity,good reproducibility and high sensitivity,the method was suitable for the determination of iodate and bromate in cosmetics.
关键词
离子色谱法柱后衍生化妆品溴酸盐碘酸盐
Keywords
ion chromatographypost-column derivatizationcosmeticsiodatebromate
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Guangdong Provincial Key Laboratory of Chemical Measurement and Emergency Test Technology,Guangdong Provincial Engineering Research Center for Quality and Safety of Traditional Chinese Medicine,Institute of Analysis,Guangdong Academy of Sciences(China National Analytical Center,),Guangzhou
Guangzhou Institute for Drug Control
Institute of Analysis,Guangdong Academy of Sciences(China National Analytical Center,Guangzhou),Guangdong Provincial Key Laboratory of Chemical Measurement and Emergency Test Technology,Guangdong Provincial Engineering Research Center for Quality and Safety of Traditional Chinese Medicine
Guangdong Institute for Drug Control,National Medical Products Administration Key Laboratory for Safety Risk Assessment of Cosmetics
Guangzhou Quality Supervision and Testing Institute,National Quality Supervision and Testing Center for Cosmetics(),Guangzhou