A rapid and effective method was developed for the determination and confirmation of five organotins，including n-butyltin-trichloride（MBT），dibutyltin-dichloride（DBT），chlorotributyl-stannane（TBT），Di-n-octyldichlorotin（DOT） and triphenyltin（TPhT），in textiles by gas chromatography tandem mass spectrometry（GC-MS/MS）.The target compounds were extracted，derivatized and liquid-liquid extracted with hexane.The qualitative and quantitative analyses were carried out by GC-MS/MS under selected reaction monitoring（SRM） mode.The test result showed that five organotins had good linear relationships（r>0.999） between 0.02 mg/L and 0.50 mg/L.The limit of quantitation（LOQ，S/N≥10） of five organotins were between 0.03 mg/kg and 0.05 mg/kg.At the spiked levels of 0.05-0.5 mg/kg in five kinds of negative samples（e.g.cotton，real silk，wool，polyester and cotton/nylon），the average recoveries of five organotins were in the range of 82%-110%， with relative standard deviations（RSD，n=5） of 2.1%- 7.5%.With high sensitivity，selectivity and good precision and accuracy,this established method could make up the shortage of confirmations by GC and GC-MS，and was suitable for the determination of different structures of organotin compounds such as mono-substituted，di-substituted and tri-substituted organotin compounds etc.，compensating for the limitation of the LC-MS/MS method which could only detect tri-substituted organotin compounds.