Indirect Determination of Anisaldehyde Dimethyl Acetal in the Process of Electrochemical Oxidation Synthesis by HPLC

您当前的位置：

首页 >

文章列表页 >

Indirect Determination of Anisaldehyde Dimethyl Acetal in the Process of Electrochemical Oxidation Synthesis by HPLC

- Indirect Determination of Anisaldehyde Dimethyl Acetal in the Process of Electrochemical Oxidation Synthesis by HPLC
- Vol. 32, Issue 5, Pages: 639-642(2013)
- 作者机构：
  
  浙江工业大学化学工程与材料/绿色化学合成技术国家重点实验室培育基地
- 作者简介：
- 基金信息：
- DOI：
  CLC：
扫描看全文
Indirect Determination of Anisaldehyde Dimethyl Acetal in the Process of Electrochemical Oxidation Synthesis by HPLC. [J]. 32(5):639-642(2013)
DOI：

Indirect Determination of Anisaldehyde Dimethyl Acetal in the Process of Electrochemical Oxidation Synthesis by HPLC. [J]. 32(5):639-642(2013) DOI：

摘要

在无水KF-CH3OH体系中直接电氧化合成的茴香醛二甲基缩醛（p-MBDMA）遇水易发生水解。研究表明在甲醇、乙腈和水的酸性混合溶液中，p-MBDMA在色谱柱中能迅速彻底地水解为茴香醛，故利用其水解反应建立了一种间接测定p-MBDMA的高效液相色谱（HPLC）方法。选择最佳流动相为水-甲醇-乙腈（50∶30∶20），用磷酸调节pH值至3.0，并探讨了测定机理。建立的HPLC测定方法准确、可靠，已应用于电化学合成p-MBDMA的分析，并可满足工业化生产的分析要求。

Abstract

The anisaldehyde dimethyl acetal （p-MBDMA） that produced by direct electrochemical oxidation synthesis in the anhydrous KF-CH3OH system is easily hydrolyzed in water.The study results indicated that p-MBDMA could be hydrolyzed into anisaldehyde raidly and completely in the acidic mixed solution of methanol，acetonitrile and water.Based on this，a high performance liquid chromatographic （HPLC） method was developed for the determination of p-MBDMA indirectly.The best mobile phase was a mixture of water-methanol-acetonitrile（50∶30∶20，adjusted pH 3.0 by phosphoric acid）.The internal mechanism of p-MBDMA in the column was also investigated.The results showed that HPLC method could be successfully applied in the rapid determination of p-MBDMA content.

关键词

高效液相色谱法电氧化合成茴香醛二甲基缩醛茴香醛间接测定

Keywords

HPLCelectrochemical oxidation synthesisanisaldehyde dimethyl acetalanisaldehydeindirect determination

references

Views

1265

下载量

CSCD

Alert me when the article has been cited

提交

Tools

Publicity Resources

Simultaneous Determination of Six Urinary Metabolites of Aromatic Compounds by HPLC

Rapid Determination of Formaldehyde in Potato Starch Noodles by High Performance Liquid Chromatography

Determination of Relative Substances in Diclofenac Sodium Gel by HPLC

Determination of Five Prohibited Coloring Agents in Cosmetics by HPLC and Their Verification by HPLC-MS/MS

Simultaneous Determination of Chlorogenic Acid and Phillyrin in ShuangHuangLian Oral Liquid and Capsule by HPLC with Online Solid Phase Extraction

Related Author

No data

Related Institution

东北大学理学院

燕山大学环境与化学工程学院河北省应用化学重点实验室

广州法尔麦兰药物技术有限公司

中国广州分析测试中心

中国检验检疫科学研究院

Address：100 Xianlie Middle Road, Guangzhou Postal code：510070
Tel：020-87684776,37656606 Fax：020-87684776 Email：fxcsxb@china.com
Technical support is provided by Beijing Founder electronics co., LTD 粤ICP备12017312号-3 京公网安备11010802024621
It is recommended to read the content of this site in Chrome&IE9+. Please switch to extreme mode in browser 360.
Cookies We use cookies to help provide and enhance our service and tailor content. By continuing, you agree to the use of cookies.

⁰