A reverse phase high performance liquid chromatographic（RP-HPLC） with variable wavelength detector(VWD) method was developed for the simultaneous determination of nine pesticide residues,including imidacloprid,acetamiprid,carbendazim, thiophanate-methyl, pyrimethanil,diflubenzuron,benzoylphenyl,phxim,avermectins in vegetables,fruit and edible fungi.The sample was extracted with acetonitrile and purified by Primary secondary amine（PSA）dispersive solid phase extraction.The analytes were separated on a C18（250 mm×4.6 mm,5 μm）column by gradient elution with methanol-acetonitrile（3∶1） and water as mobile phase,and detected at the wavelengths of 270,258,275,254,280,245 nm,respectively.The flow rate was set at 1.0 mL/min and the column temperature was 40 ℃.The results indicated that the calibration curves of nine pesticides showed good linear relationships in the concentration of 0.05-10.0 mg/L with correlation coefficients more than 0.999.The detection limits ranged from 0.006 mg/kg to 0.07 mg/kg.The recoveries ranged from 81.0% to 115.2% with relative standard deviations（RSD） of 0.5%-10.2%.The method was simple,rapid,sensitive and accurate,and was suitable for the determination of the above 9 pesticide residues in vegetables,fruit and edible fungi.