Monodisperse macroporous poly（glycidylmethacrylate-co-ethylenedimethacrylate） （PGMA/EDMA） beads were synthesized,and a new kind of strong anion stationary phase was prepared by chemical modification of the PGMA/EDMA beads.This column has a superior separation ability for some inorganic anions（e.g.F-,Cl-,NO-2,Br-,NO-3 and SO2-4） and organic acids（e.g.methane acid,acetic acid,monochloroacetic acid and oxalic acid） by elution of 6.0 mmol/L sodium carbonate and 5.5 mmol/L sodium bicarbonate at a flow rate of 1.0 mL/min.Moreover,the separation of a mixture of anions and organic acids can also be well obtained at the same chromatographic conditions.The influences of eluent type,pH value and organic solvent on retention of six inorganic anions were studied.Under the optimized chromatorgraphic conditions,the six anions had good linear relationships in the certain concentration range and low detection limits.The column was used in the separation of inorganic anions in running water,and four anions were separated in 22 min.The recoveries of four anions were between 96.4% and 100.6%.