A method to discriminate the quality grade of Minnan oolong tea Tieguanyin was developed based on comprehensive two-dimensional gas chromatography-time-of-flight mass spectrometry（GC×GC-TOF MS） coupled with cluster analysis and Fishers discriminate analysis.Samples of different qualities and production seasons from Anxi county were collected and extracted with acetone.The extracts were filtrated with activated carbon,and then analyzed by GC×GC-TOF MS.More than 1 000 peaks were obtained for each sample,which were used for the quality analysis.Among the compounds obtained,68 common compounds were detected from 24 different quality grades of Tieguanyin,and they were tentatively identified with comparison to the standard mass spectra in available databases,retention index and structured chromatogram for further analysis using IBM SPSS Statistics 19.Based on these common compounds,the scatter plot from cluster analysis based on Ward method presented a straightforward classified information for different grades of Tieguanyin tea.In addition,5 compounds which had significant impacts on the classification were selected using stepwise discriminate analysis,and these compounds were used as variables to establish 4 discriminated functions by Fisher’s discriminate analysis.The compliance for recognition of 24 tea samples was 95.8% obtained by Fisher’s discriminate analysis.The results demonstrated that the developed method could be used to discriminate the quality grade of Tieguanyin with reliability.