Simultaneous Determination of Total Specific Migration Limit of 9 Types of Ultraviolet Absorbers in Food Simulants by High Performance Liquid Chromatography-Tandem Mass Spectrometry
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Simultaneous Determination of Total Specific Migration Limit of 9 Types of Ultraviolet Absorbers in Food Simulants by High Performance Liquid Chromatography-Tandem Mass Spectrometry
Vol. 34, Issue 9, Pages: 1021-1026(2015)
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台州出入境检验检疫局
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Simultaneous Determination of Total Specific Migration Limit of 9 Types of Ultraviolet Absorbers in Food Simulants by High Performance Liquid Chromatography-Tandem Mass Spectrometry. [J]. 34(9):1021-1026(2015)
DOI:
Simultaneous Determination of Total Specific Migration Limit of 9 Types of Ultraviolet Absorbers in Food Simulants by High Performance Liquid Chromatography-Tandem Mass Spectrometry. [J]. 34(9):1021-1026(2015)DOI:
Simultaneous Determination of Total Specific Migration Limit of 9 Types of Ultraviolet Absorbers in Food Simulants by High Performance Liquid Chromatography-Tandem Mass Spectrometry
A novel method for the simultaneous determination of total specific migration limit of UV-24,UV-0,UV-9,DHBP,UV-531,HHBP,UV-P,UV-327 and UV-326 in food simulants(10% ethanol,20% ethanol,50% ethanol,3% acetic acid and olive oil) was developed using high performance liquid chromatography-tandem mass spectrometry(HPLC-MS/MS).After the migration test,the soaking solution was cooled down,and homogenized.Olive oil food simulant was extracted with acetonitrile and n heptane,the clear acetonitrile solution and other aqueous food stimulant diluted with ethanol(1∶10) were filtered through a hydrophilic polytetrafluoroethylene filter with a disposable syringe before injection.The SunFireTM C8 column and gradient elution were selected to separate.The AB Qtrap 4500 tandem quadrupole mass spectrometer was operated under multiple reaction monitoring(MRM) and ESI-mode.The limits of quantitation were between 0.01 mg/kg and 0.30 mg/kg.The linearity of the method was good with correlation coefficients(r) not less than 0.995 4 over the certain concentration range .The recoveries at spiked concentration levels of 1-35 mg/kg were between 80.0% and 127% with relative standard deviations of 0.8%-8.0%.With the high sensitivities,good recoveries and accuracies,the method could be applied for the analysis of food contact material samples.
关键词
高效液相色谱-串联质谱(HPLC-MS/MS)紫外吸收剂特定总迁移量食品模拟物
Keywords
high performance liquid chromatography-tandem mass spectrometry(HPLC-MS/MS)ultraviolet absorbentstotal specific migration limitfood simulants
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Related Institution
Technology Center of Haikou Customs
Department of Food Science and Engineering,Jinan University
National Reference Laboratory of Food Contact Material(Guangdong),Guangzhou Customs Technology Center
Key Laboratory of Product Packaging and Logistics of Guangdong Higher Education Institutes,College of Packaging Engineering,Jinan University