Research Progress for Analytical Methods of Adenosine Deaminase Activity

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Research Progress for Analytical Methods of Adenosine Deaminase Activity

- Research Progress for Analytical Methods of Adenosine Deaminase Activity
- Vol. 35, Issue 9, Pages: 1209-1216(2016)
- 作者机构：
  
  1. 天津大学药物科学与技术学院
  2. 天津市现代药物传递及功能高效化重点实验室
  3. 天津化学化工协同创新中心
- 作者简介：
- 基金信息：
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Research Progress for Analytical Methods of Adenosine Deaminase Activity. [J]. 35(9):1209-1216(2016)
DOI：

Research Progress for Analytical Methods of Adenosine Deaminase Activity. [J]. 35(9):1209-1216(2016) DOI：

摘要

腺苷脱氨酶(ADA)是一种核酸代谢酶，与机体细胞免疫活性有重要关系，在很多疾病中，ADA活性均表现异常。因此，越来越多的科研工作者聚焦于ADA活性与疾病关系的研究，并一致认为ADA活性分析对临床疾病的诊断与治疗具有非常重要的意义。该文综述了比色法、色谱法、适配体传感器等ADA活性分析方法的研究进展，以期为ADA的活性分析提供参考。

Abstract

Adenosine deaminase(ADA)， a kind of catabolic enzymes toward nucleic acid,has a close relationship with cell immunocompetence.ADA activity is abnormal in many diseases.Therefore，more and more researchers have been focusing on research of the relationship between ADA activity and some diseases.Analysis of the ADA activity is considered to has a very important significance in clinical diagnosis and treatment of diseases.Currently，many reports about novel analysis methods of ADA activity have been published，but no relevant reviews have been reported so far.In this paper，analytical methods of ADA activity such as colorimetric，chromatography and adapter sensor methods，are summarized，which is expected to provide references for the analysis of ADA.

关键词

腺苷脱氨酶活性分析临床检测色谱适配体传感器

Keywords

adenosine deaminaseactivity analysisclinical testchromatographyadapter sensor

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Faculty of Materials Science and Chemistry，China University of Geosciences

State Key Laboratory of Biogeology and Environmental Geology，China University of Geosciences

齐鲁工业大学(山东省科学院)药学院

齐鲁工业大学(山东省科学院)山东省分析测试中心山东省大型精密分析仪器应用技术重点实验室

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