A new method was developed for the determination of 10 kinds of salicylamides，including 5-chlorosalicylanilid，4′-bromosalicylanilid，3′,4′-dichloro-salicylanilid，4′,5-dichloro-salicylanilid，3′,4′,5-trichloro-salicylanilid，5-bromo-4′-chlorosalicylanilide，3,5-dibromo-salicylanilid，4′,5-dibromo-salicylanilid，3,4′,5-tribromo-salicylanilid and 3,3′,4′,5-tetrachloro-salicylanilid in foods of animal origin using solid phase extraction（SPE） combined with ultra-performance liquid chromatography-tandem mass spectrometry（HPLC-MS/MS）.Samples were extracted using acetonitrile, and purified with an amino（NH2） SPE column. The eluent was concentrated by nitrogen gas blowing.10 target compounds were separated on a T3 column（100mm×2.1mm，1.8μm） by gradient elution with methanol-0.1% formic acid as mobile phase，ionized by negative electrospray ionization（ESI-），detected under multiple reaction monitoring（MRM） mode，and quantified by the external standard method. Under the optimized condition，the calibration curves of 10 kinds of salicylamides were linear in a certain concentration range with correlation coefficients（r2） no less than 0.9957.The limits of detection（LODs，S/N=3） and limits of quantitation（LOQs，S/N=10） for the target compounds were in the ranges of 0.5-1.0μg/kg and 1.5-3.0μg/kg，respectively. The average recoveries at three spiked levels ranged from 81.0% to 106%，with relative standard deviations（RSD，n=6） no more than 7.5%.The method was suitable for the identification and quantification of 10 kinds of salicylamides in foods of animal origin.