Time-of-flight mass spectrometry(TOF-MS) is a kind of mass spectrometric technique with high scan speed,wide scan range,high sensitivity and high mass resolution abilities.Compared with the conventional ion trap and quadruple mass spectrometry,TOF-MS has higher qualitative and throughput screening abilities.The applications of qualitation and quantitation on pesticide residues in the field of quality and safety on agricultural products have become more and more important.With the continued improvement and development of TOF-MS technique,it has been considered a powerful research tool for researchers.In this paper,the literatures on TOF-MS applications in analysis of pesticide residues in fruit,vegetable and tea,published at home and abroad since 2010，are reviewed in three aspects where it is coupled with gas chromatography,liquid chromatography and convergence chromatography.The development prospect of this TOF-MS technique in pesticide residue analysis of fruits,vegetables and tea is also prospected.