Non-target Screening of Illegal Additive Residues in Herbal Teas by High Performance Liquid Chromatography-Quadrupole-Time-of-Flight Mass Spectrometry with QuEChERS Purification
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Non-target Screening of Illegal Additive Residues in Herbal Teas by High Performance Liquid Chromatography-Quadrupole-Time-of-Flight Mass Spectrometry with QuEChERS Purification
Vol. 38, Issue 4, Pages: 429-434(2019)
作者机构:
1. 广东检验检疫技术中心
2. 广东省动植物与食品进出口技术措施研究重点实验室
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Non-target Screening of Illegal Additive Residues in Herbal Teas by High Performance Liquid Chromatography-Quadrupole-Time-of-Flight Mass Spectrometry with QuEChERS Purification. [J]. 38(4):429-434(2019)
DOI:
Non-target Screening of Illegal Additive Residues in Herbal Teas by High Performance Liquid Chromatography-Quadrupole-Time-of-Flight Mass Spectrometry with QuEChERS Purification. [J]. 38(4):429-434(2019)DOI:
Non-target Screening of Illegal Additive Residues in Herbal Teas by High Performance Liquid Chromatography-Quadrupole-Time-of-Flight Mass Spectrometry with QuEChERS Purification
A high performance liquid chromatography-quadrupole-time of flight mass spectrometric(HPLC-Q-TOF/MS)method with a modified QuEChERS purification was developed for the rapid screening of unkown illegal additive residues in herbal teas.The target compounds in samples were extracted with 0.5%acetic acid-acetonitrile,cleaned with NH2 sorbent and separated on a C18 column(100 mm×2.1 mm,1.7 μm),then determined by HPLC-Q-TOF/MS.The detection limits and the quantitation limits for 8 control drugs were in the ranges of 2.0-10 μg/kg and 5.0-25 μg/kg,respectively.The average recoveries for the samples at three spiked levels ranged from 75.8%to 95.6%,with RSD(n=6)of 2.1%-6.5%.Moreover,the acquired data were compared with the library using the accurate mass,isotopic distribution,fragmentation information to screen illegal additive residues in herbal teas without reference standards.The developed method was used in the determination of 50 herbal tea samples.Results showed that paracetamol was detected in 10 samples,with content range of 4.14-2 188 mg/kg.This method is efficient,sensititive and accurate,and could meet the requirement for rapid screening of unkown illegal additive residues in herbal teas.
Determination of 10 N-Nitrosamines in Cosmetics by QuEChERS/Gas Chromatography-Tandem Mass Spectrometry
Rapid and Simultaneous Analysis of 11 Adulterated Drugs in Herbal Tea by HPLC
Analysis of Thiamethoxam,Clothianidin and Spirotetramat and Their Metabolites Residues in Tomato Using QuEChERS Method with Ultra Performance Liquid Chromatography-Mass Spectrometry