In this work

Ag nanoparticles/multi walled carbon nanotubes(AgNPs/MWCNTs) composites were synthesized with multi walled carbon nanotubes(MWCNTs) and silver nitrate as raw materials

and sodium borohydride as reduction agent

and the AgNPs/MWCNTs composites were characterized by ultraviolet visible absorption spectroscopy

infrared spectroscopy

Raman spectroscopy and X-ray diffraction.Based on this

an Ag nanoparticles/multi walled carbon nanotubes modified electrode(AgNPs/MWCNTs/GCE) was prepared by immobilizing AgNPs/MWCNTs onto the surface of glassy carbon electrode.Effects of buffer solution

pH value，supporting electrolyte and scanning rate on electrochemical reactivity of the AgNPs/MWCNTs/GCE were investigated.Results showed that the nanocomposite modified electrode had a better electrocatalytic activity for sulfamethoxazole(SMZ)

compared with MWCNTs or Ag nanoparticles modified electrode.Under the optimized conditions

there was a linear relationship between SMZ and peak current in the range of 3.0×10-7-5.0×10-5 mol/L

and the limit of detection(S/N=3) was 6.4×10-8 mol/L.The method is simple and rapid

and could be used for the detection of SMZ in river samples.