王荣, 刘艳芳, 王超然, 郭志谋, 梁鑫淼. Research Progress on High Performance Liquid Chromatography in Analysis and Preparation of Alkaloids[J]. 2019, 38(5): 586-594.DOI: doi:10.3969/j.issn.1004-4957.2019.05.014.
Alkaloids are a class of natural compounds with good pharmacological properties.In the field of separation science and technology
alkaloid separation has always been a hot and difficult problem.In recent years
with the development of high performance liquid chromatography(HPLC) materials and separation methods
great progresses in alkaloid analysis and preparation have been achieved.In this article
the theoretical development and technological advances with respect to peak tailing problems of basic compounds are summarized
and the applications of HPLC in natural alkaloid analysis and preparation are discussed.The further development of HPLC separation on alkaloids is also looked forward.