浏览全部资源
扫码关注微信
1.天津中医药大学 中药制药工程学院,天津 301617
2.天士力医药股份有限公司 中药先进制造技术国家地方联合工程实验室,天津 300410
3.成都康弘药业集团股份有限公司,四川 成都 610037
章顺楠,博士,研究员,研究方向:中药国际化与智能制造,E-mail:zsn@tasly.com
李文龙,博士,研究员,研究方向:中药质量控制技术研究,E-mail:wshlwl@tjutcm.edu.cn
收稿日期:2025-02-21,
修回日期:2025-03-15,
录用日期:2025-03-20,
纸质出版日期:2025-06-15
移动端阅览
冯佳豪,关志琪,张智勇,陈景超,章顺楠,李文龙.基于近红外光谱与化学计量学的淫羊藿与柔毛淫羊藿基原鉴别及模型转移研究[J].分析测试学报,2025,44(06):1034-1042.
FENG Jia-hao,GUAN Zhi-qi,ZHANG Zhi-yong,CHEN Jing-chao,ZHANG Shun-nan,LI Wen-long.Study on Source Identification and Model Transfer of Epimedium Brevicornum and Epimedium Pubescens Based on Near Infrared Spectroscopy and Chemometrics[J].Journal of Instrumental Analysis,2025,44(06):1034-1042.
冯佳豪,关志琪,张智勇,陈景超,章顺楠,李文龙.基于近红外光谱与化学计量学的淫羊藿与柔毛淫羊藿基原鉴别及模型转移研究[J].分析测试学报,2025,44(06):1034-1042. DOI: 10.12452/j.fxcsxb.250221109.
FENG Jia-hao,GUAN Zhi-qi,ZHANG Zhi-yong,CHEN Jing-chao,ZHANG Shun-nan,LI Wen-long.Study on Source Identification and Model Transfer of Epimedium Brevicornum and Epimedium Pubescens Based on Near Infrared Spectroscopy and Chemometrics[J].Journal of Instrumental Analysis,2025,44(06):1034-1042. DOI: 10.12452/j.fxcsxb.250221109.
基于近红外光谱结合化学计量学方法,针对淫羊藿与柔毛淫羊藿的基原鉴别及模型转移进行了系统研究。首先,通过主成分分析(PCA)探讨两者的光谱差异,为后续分类建模提供参考。随后,建立支持向量机(SVM)和随机森林(RF)分类模型,并对比不同光谱预处理方法的影响,筛选出最佳预处理组合(SG+1
st
Der+SNV和 SG+2
nd
Der+SNV),最终获得高准确率的基原鉴别模型(鉴别准确率为100%)。在此基础上,采用直接校正法(DS)和分段直接校正法(PDS)对模型进行校正,并通过层次聚类(HC)方法选择标准样品,成功提高了模型的适应性和迁移效果。研究结果表明,SVM模型在分类准确率和迁移稳定性方面均优于RF模型,为便携式近红外光谱仪在中药基原鉴别中的应用提供了科学依据。
Based on near infrared spectroscopy combined with chemometrics methods,this study systematically studied the origin identification and model transfer of
Epimedium brevicornum
and
Epimedium pubescens
. Firstly,principal component analysis(PCA) was used to explore the spectral differences between the two,which provides a reference for subsequent classification modeling. Subsequently,support vector machine(SVM) and random forest(RF) classification models were established,and the effects of different spectral preprocessing methods were compared to screen out the best preprocessing combination(SG+1
st
Der+SNV and SG+2
nd
Der+SNV). Finally,a high-accuracy primitive identification model(the identification accuracy was 100%) was obtained. On this basis,the DS and PDS methods were used to correct the model,and the standard samples were selected by hierarchical clustering(HC),which successfully improved the adaptability and migration effect of the model. The results showed that the SVM model was superior to the RF model in terms of classification accuracy and migration stability,which provided a scientific basis for the application of portable near infrared spectrometer in the identification of traditional Chinese medicine.
Wang H Y , Zhang Y H , Li H X . Henan Tradit. Chin. Med. (王涵玉 , 张宇航 , 李焕香 . 河南中医) , 2024 ,( 11 ): 1765 - 1771 .
Li M , Liu F Y , Ding D N , Han F J . Inf. Tradit. Chin. Med. (李敏,刘芳媛,丁丹妮,韩凤娟. 中医药信息), 2024 , 41 ( 3 ): 71 - 76 .
Hao Q F , Yuan P W , Meng Q H , Zhao Y F , Liu D Y , Wang Z K , Yu H C . China Med. Her. (郝庆飞,袁普卫,孟庆豪,赵怡凡,刘德玉,王占魁,余红超. 中国医药导报), 2024 , 21 ( 10 ): 189 - 192 .
Yu Y Y . Chin. J. Public Health Eng. (于洋洋. 中国卫生工程学), 2024 , 23 ( 6 ): 859 - 860,864 .
Zhang Y , Li J , Wang Y , Liang Q . Chin. Herb. Med. , 2021 , 14 ( 1 ): 20 - 35 .
Tang T , Tan T Y , Liu Z J , Bai X . Chin. J. Pharmacovigilance (唐田,谭天阳,刘柘君,白雪. 中国药物警戒), 2024 , 21 ( 11 ): 1238 - 1242 .
Yu W L , Zhang H . China Med. Pharm. (于玟路,张虹. 中国医药科学), 2024 , 14 ( 21 ): 32 - 35,39 .
Fan X L , Luo Y J , Xu C Q , Guo B L . Bull. Bot. (范雪兰,落艳娇,徐超群,郭宝林. 植物学报), 2024 , 59 ( 5 ): 834 - 846 .
Liu X , Wang M Y , Lu F J . Guangdong Chem. Ind. (刘璇,王梦悦,卢方晋. 广东化工), 2024 , 51 ( 8 ): 132 - 134,118 .
Zhang W Z , Li C P , Chen L , Guo D M , Li J , Zhang Y Y , Wei K B , Zhang Y . Chin. Health Care (张文正,李纯璞,陈蕾,郭冬梅,李军,张媛媛,魏开斌,张亚. 中华养生保健), 2024 , 42 ( 5 ): 81 - 85,92 .
Bi Z , Zhang W , Yan X . Biomed. Pharmacother. , 2022 , 151 : 113180 .
Zhao Y D , Zhang X , Yang W Y , Zhang R Q , Mu L T , Han L , Lv C N , Lu J C . Chin. J. Nat .Med. , 2022 , 20 ( 3 ): 221 - 228 .
Yin S J , Luo H , Sun X L , Zhou L X . Shandong Chem . Ind. (尹素娟,骆航,孙兴力,周联选. 山东化工), 2024 , 53 ( 15 ): 178 - 183 .
Wu S J , Wang L , Wu H G , He X L , Qiu P , Li Z , Li W L . J. Instrum. Anal. (吴思俊,王龙,吴红根,贺兴立,仇萍,李正,李文龙. 分析测试学报), 2022 , 41 ( 1 ): 121 - 127 .
Zhang Z Y , Wu S J , Qiu P , Peng X S , Li Z , Li W L . Cent. South Pharm. (张智勇,吴思俊,仇萍,彭晓珊,李正,李文龙. 中南药学), 2019 , 17 ( 9 ): 1431 - 1435 .
Chen P , Yang J , Chu X L , Li J Y , Xu Y P , Liu D . Chin. J. Anal. Chem. (陈瀑,杨健,褚小立,李敬岩,许育鹏,刘丹. 分析化学), 2024 , 52 ( 9 ): 1213 - 1224 .
Xiong H S , Tian G , Liu P , Zhao W S , Li C M , Zhu Y H , Ye Z L , Zhang S N , Yan K J . Chin. Herb. Med. (熊皓舒,田埂,刘朋,赵万顺,李晨鸣,朱永宏,叶正良,章顺楠,闫凯境. 中草药), 2020 , 51 ( 16 ): 4331 - 4337 .
Pan X , Liu H , Wang H , Liu J , He Y L , Huang W C , Qiu C G . J. Instrum. Anal. (潘曦,刘辉,王昊,刘静,何昀潞,黄伟初,邱昌桂. 分析测试学报), 2020 , 39 ( 11 ): 1385 - 1391 .
Kong Q Q , Ding X Q , Gong H L , Li Z R , Tang X H , Yu C X . J. Instrum. Anal. (孔清清,丁香乾,宫会丽,李忠任,唐兴宏,于春霞. 分析测试学报), 2017 , 36 ( 10 ): 1203 - 1207 .
0
浏览量
4
下载量
0
CSCD
关联资源
相关文章
相关作者
相关机构