基于聚中性红/SnO<sub>2</sub> II型异质结的卡那霉素光电化学适体传感

杨华; 邵孜琦; 曾星宇; 翁雅情; 李嘉慧; 谢青季

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基于聚中性红/SnO₂ II型异质结的卡那霉素光电化学适体传感

研究报告 | 更新时间：2026-04-29

- 基于聚中性红/SnO₂ II型异质结的卡那霉素光电化学适体传感
- Photoelectrochemical Aptasensing of Kanamycin Based on a Poly(Neutral Red)/SnO₂ Type-II Heterojunction
- 分析测试学报 2026年
- 作者机构：
  
  1.湖南师范大学化学化工学院化学生物学及中药分析教育部重点实验室，湖南长沙 410081
  2.山东省淄博生态环境监测中心,山东淄博 255022
- 作者简介：
  
  邵孜琦，硕士，研究方向：环境分析，E-mail: szq990115@163.com
  谢青季，博士，教授，研究方向：电化学分析，E-mail: xieqj@hunnu.edu.cn.
- 基金信息：
  
  国家自然科学基金资助项目(22474035;22074039)
- DOI：
  中图分类号：
- 收稿：2026-03-03，
  
  修回：2026-03-14，
  
  录用：2026-04-11，
- 稿件说明：
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杨华, 邵孜琦, 曾星宇, 翁雅情, 李嘉慧, 谢青季. 基于聚中性红/SnO₂ II型异质结的卡那霉素光电化学适体传感[J/OL]. 分析测试学报, 2026.

YANG Hua, SHAO Zi-qi, ZENG Xing-yu, Weng Ya-qing, LI Jia-hui, XIE Qing-ji. Photoelectrochemical Aptasensing of Kanamycin Based on a Poly(Neutral Red)/SnO₂ Type-II Heterojunction[J/OL]. Journal of Instrumental Analysis, 2026.
杨华, 邵孜琦, 曾星宇, 翁雅情, 李嘉慧, 谢青季. 基于聚中性红/SnO₂ II型异质结的卡那霉素光电化学适体传感[J/OL]. 分析测试学报, 2026. DOI：

YANG Hua, SHAO Zi-qi, ZENG Xing-yu, Weng Ya-qing, LI Jia-hui, XIE Qing-ji. Photoelectrochemical Aptasensing of Kanamycin Based on a Poly(Neutral Red)/SnO₂ Type-II Heterojunction[J/OL]. Journal of Instrumental Analysis, 2026. DOI：

摘要

通过水热法合成SnO

纳米颗粒并将其滴涂到掺氟氧化锡（FTO）上，再通过循环伏安法在电极上电聚合中性红（NR）成聚中性红（PNR）薄膜，制得PNR/SnO

/FTO光阳极。利用含氨基PNR和氨基化卡那霉素（KAN）适体（Apt）与戊二醛（GLD）交联剂的席夫碱反应，制得Apt/GLD/PNR/SnO

/FTO光阳极。基于Apt特异性识别KAN所致构象变化和空间位阻效应，实现了KAN的高敏PEC适体传感。利用光谱学、电化学和电子显微镜等法对所制材料和电极进行了表征。优化实验条件后，阳极光电流变化值与0.01 nM ~ 750 nM范围的KAN浓度的常用对数值呈良好的线性关系，检测下限（LOD，

= 3）为3 pM。将该法用于实际牛奶样品中KAN的检测获较好的回收率结果。

Abstract

A poly(neutral red) (PNR)/SnO

type-II heterojunction was prepared by cyclic voltammetry electropolymerization of neutral red (NR) on a fluorine-doped tin oxide (FTO) electrode that had been cast-coated with hydrothermally synthesized SnO

. An Apt/GLD/PNR/SnO

/FTO photoanode was prepared after the Schiff base reaction among aminated kanamycin (KAN) aptamer (Apt)

glutaraldehyde (GLD)

and amino group-bearing PNR

and the signal attenuation photoelectrochemistry analysis of KAN was then realized on the basis of the steric hindrance effect induced by the specific KAN-Apt binding. Under optimal conditions

the decline value of anodic photocurrent was linearly related to the common logarithm of KAN concentration from 0.01 nM to 750 nM

with a limit of detection (

=3) of 3 pM. Satisfactory recov

eries were obtained for analysis of KAN in milk samples.

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Photoelectrochemical Aptasensing of Kanamycin Based on a Poly(Neutral Red)/SnO2 Type-II Heterojunction

DOI：

摘要

Abstract

关键词

Keywords

references

基于聚中性红/SnO₂ II型异质结的卡那霉素光电化学适体传感

Photoelectrochemical Aptasensing of Kanamycin Based on a Poly(Neutral Red)/SnO₂ Type-II Heterojunction