LI Gui-xiao,YIN Chang,WANG Yue,FAN Hong-mei,PENG Xiao-hui,HE Xiang-ke,GAO Cui-ling.Determination of Glyceryl Glucoside in Cosmetics by High Performance Anion Exchange Chromatography-Integrated Pulse Amperometry[J].Journal of Instrumental Analysis,2025,44(07):1439-1442.
LI Gui-xiao,YIN Chang,WANG Yue,FAN Hong-mei,PENG Xiao-hui,HE Xiang-ke,GAO Cui-ling.Determination of Glyceryl Glucoside in Cosmetics by High Performance Anion Exchange Chromatography-Integrated Pulse Amperometry[J].Journal of Instrumental Analysis,2025,44(07):1439-1442. DOI: 10.12452/j.fxcsxb.241114526.
Determination of Glyceryl Glucoside in Cosmetics by High Performance Anion Exchange Chromatography-Integrated Pulse Amperometry
A method for determination of glyceryl glucoside in cosmetics was established in this paper. The sample is extracted with 10% methanol water by ultrasonic extraction and vortex shaking,and the supernatant was filtered through a filter membrane before being tested on the instrument. The system used was a Hamilton RCX-30 anion exchange column,a pulse amperometric detector,a gold working electrode,a flow rate of 1 mL/min,ion chromatography measurement,and external standard quantification. The extraction solvent,extraction time,matrix effect were analyzed and studied. The results showed that glyceryl glucoside had good linearity within the concentration range of 0.1-5.0 mg/L,with recoveries of 96.0%-108% and relative standard deviations of 1.2%-5.0%,and correlation coefficient of 0.999 7. The detection limit is 0.2 mg/kg. The method is simple,efficient,and has good repeatability and stability,making it suitable for the accurate determination of glyceryl glucoside in cosmetics.
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