REN Shu-fang,LIU Ya-hui,CAO Li,WANG Zi-han,CHEN Yu,LIU Di.Construction of an Electrochemical Sensor Based on UiO-66-NH2 Metal-Organic Framework Composite with MWCNTs for Morphine Detection[J].Journal of Instrumental Analysis,2025,44(07):1313-1320.
REN Shu-fang,LIU Ya-hui,CAO Li,WANG Zi-han,CHEN Yu,LIU Di.Construction of an Electrochemical Sensor Based on UiO-66-NH2 Metal-Organic Framework Composite with MWCNTs for Morphine Detection[J].Journal of Instrumental Analysis,2025,44(07):1313-1320. DOI: 10.12452/j.fxcsxb.241112522.
Construction of an Electrochemical Sensor Based on UiO-66-NH2 Metal-Organic Framework Composite with MWCNTs for Morphine Detection
) were prepared using hydrothermal and composite materials of UiO-66-NH
2
/multi-walled carbon nanotubes(MWCNTs) were formed using ultrasonic mechanical mixing method. An electrochemical sensor was constructed using the drop-coating method. The composition and morphological structure of the materials were analyzed using X-ray diffraction,field emission scanning electron microscopy,field emission transmission electron microscope and Fourier-transform infrared spectroscopy. The electrochemical performance of the modified electrode was
investigated using cyclic voltammetry with potassium ferricyanide as the electron probe,and the electrochemical response of the electrode to morphine was examined using pulse voltammetry. The detection conditions,such as the mass ratio of the modified materials,enrichment time,and pH were optimized. The constructed sensor exhibited a high electrochemical response to morphine,with a linear detection range of 10-100 μmol/L and a minimum detection limit(
S
/
N
=3)of 9.922 μmol/L. The sensor demonstrated good stability,repeatability(RSD=4.1%),and anti-interference ability(RSD
<
5.0%). The standard addition method was used to detect morphine in sweat and urine samples with recoveries of 92.1%-98.4% and RSD(
n
=3) below 5.0%.
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